Comparison of external lung monitoring with end-tidal air detection using the 133xenon inhalation method.
Comparison of external lung monitoring with end-tidal air detection using the 133xenon inhalation method.
复制标题
使用 133 氙吸入法进行肺外监测与呼气末空气检测的比较。
作者：
Hazelrig,JB;HalseyJr,JH;Wilson,EM;Wills,EL
当采用133氚吸入法测量局部脑血流量时，动脉133氚浓度通常近似于潮气末空气浓度。然而，在存在某些肺部病变或呼吸模式不规则时，这种近似可能无效。Jaggi和Obrist使用静脉注射133氚，提出一旦从信号中去除133氚在浅表组织中产生的噪声，由外部肺探头检测的计数可以提供动脉血浓度的替代估计。一个数学模型，类似于他们的假设的基础上，在这里提出了一个新的计算程序，用于消除噪声。对10名健康年轻男性进行的正常休息研究的结果表明，当吸入133？时，从潮气末空气和校正的肺计数获得的动脉血浓度的近似值是不相等的。浓度-时间曲线具有不同的形状，这些差异反映在头部通道计算的血流量值中。然而，对左右半球同源区域之间的比较没有影响。
When the 133Xe inhalation method is employed for measuring regional cerebral blood flow, the arterial 133Xe concentration is usually approximated by the end-tidal air concentration. However, this approximation may be invalid in the presence of certain lung pathologies or when the breathing pattern is irregular. Jaggi and Obrist, using an intravenous injection of 133Xe, suggested that the counts detected by an external lung probe could provide an alternative estimate for arterial blood concentration once the noise produced by 133Xe in superficial tissues is removed from the signal. A mathematical model, based on hypotheses similar to theirs is presented here together with a new computational procedure for removing the noise. Results from normal rest studies on ten healthy young males indicate that the approximations for arterial blood concentration obtained from end-tidal air and from corrected lung counts are not equivalent when 133Xe is administered by inhalation. The concentration-time curves have different shapes, and these differences are reflected in blood flow values computed by head channel. However, there is no effect on comparisons between homologous regions of the left and right hemispheres.
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影响因子：
20.1
作者：
SEVERINGHAUS, JW;CHIODI, H;HORNBEIN, TF
通讯作者：
HORNBEIN, TF
通过在线计算机133氙吸入法测量局部血流量。
影响因子：
7.7
作者：
E. M. Wilson;E. Wills;J. Risberg;J. Halsey;J. Gerard;C. P. May
通讯作者：
C. P. May
影响因子：
20.1
作者：
W. Obrist;H. Thompson;Herschel King;H. Wang
通讯作者：
H. Wang
通过吸入 133 氙来估算局部脑血流量。
影响因子：
8.3
作者：
W. Obrist;H. Thompson;H. Wang;W. Wilkinson
通讯作者：
W. Wilkinson