Resistance exercise as a treatment for sarcopenia: prescription and delivery.
Resistance exercise as a treatment for sarcopenia: prescription and delivery.
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DOI：
10.1093/ageing/afac003
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发表时间：
2022-02-02
期刊：
影响因子：
6.7
通讯作者：
Sayer AA
中科院分区：
文献类型：
--
作者：
Hurst C;Robinson SM;Witham MD;Dodds RM;Granic A;Buckland C;De Biase S;Finnegan S;Rochester L;Skelton DA;Sayer AA
肌肉减少症是一种全身性骨骼肌疾病，其特征是肌肉力量和质量降低，并与一系列负面健康结果相关。目前，抗阻运动（RE）被推荐为一线治疗，以抵消老年人肌肉减少症的有害后果。然而，虽然有相当多的证据表明RE是改善健康老年人肌肉力量和功能的有效干预措施，但对患有肌肉减少症的老年人的益处知之甚少。此外，其最佳处方和交付的证据非常有限，在没有适当运动剂量的情况下，RE的任何潜在益处都不太可能实现。我们提供了一个有效的RE处方（特异性，超负荷和进展）的基本原则的总结，并讨论了设计RE方案时可以操纵的主要变量（训练频率，运动选择，运动强度，运动量和休息时间）。在此之后，我们建议每周两次运动，包括上半身和下半身运动的组合，以相对较高的努力进行1-3组6-12次重复的RE计划适合作为肌肉减少症的治疗。本文概述的RE处方原则和本文提出的RE计划为临床医生和运动从业者治疗老年人肌肉减少症提供了有用的资源，也将对研究人员在未来肌肉减少症研究中标准化RE干预方法具有价值。
Sarcopenia is a generalised skeletal muscle disorder characterised by reduced muscle strength and mass and associated with a range of negative health outcomes. Currently, resistance exercise (RE) is recommended as the first-line treatment for counteracting the deleterious consequences of sarcopenia in older adults. However, whilst there is considerable evidence demonstrating that RE is an effective intervention for improving muscle strength and function in healthy older adults, much less is known about its benefits in older people living with sarcopenia. Furthermore, evidence for its optimal prescription and delivery is very limited and any potential benefits of RE are unlikely to be realised in the absence of an appropriate exercise dose. We provide a summary of the underlying principles of effective RE prescription (specificity, overload and progression) and discuss the main variables (training frequency, exercise selection, exercise intensity, exercise volume and rest periods) that can be manipulated when designing RE programmes. Following this, we propose that an RE programme that consists of two exercise sessions per week and involves a combination of upper- and lower-body exercises performed with a relatively high degree of effort for 1–3 sets of 6–12 repetitions is appropriate as a treatment for sarcopenia. The principles of RE prescription outlined here and the proposed RE programme presented in this paper provide a useful resource for clinicians and exercise practitioners treating older adults with sarcopenia and will also be of value to researchers for standardising approaches to RE interventions in future sarcopenia studies.
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DOI：
10.1186/s11556-021-00277-7
发表时间：
2021-11-11
期刊：
European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity
影响因子：
--
作者：
Chen N;He X;Feng Y;Ainsworth BE;Liu Y
通讯作者：
Liu Y
影响因子：
5.8
作者：
Dent, E.;Morley, J. E.;Vellas, B.
通讯作者：
Vellas, B.
影响因子：
9.8
作者：
Buckner, Samuel L.;Jessee, Matthew B.;Loenneke, Jeremy P.
通讯作者：
Loenneke, Jeremy P.
影响因子：
3.4
作者：
Buckley, John P.;Borg, Gunnar A. V.
通讯作者：
Borg, Gunnar A. V.
DOI：
10.22540/jfsf-03-105
发表时间：
2018-06-01
期刊：
Journal of frailty, sarcopenia and falls
影响因子：
--
作者：
Cavill, Nick A;Foster, Charlie E M
通讯作者：
Foster, Charlie E M