COVID-19 vaccine acceptance among health care workers in Africa: A systematic review and meta-analysis.
COVID-19 vaccine acceptance among health care workers in Africa: A systematic review and meta-analysis.
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DOI：
10.1371/journal.pone.0268711
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Boakye, Hosea
中科院分区：
文献类型：
--
作者：
Ackah, Martin;Ameyaw, Louise;Salifu, Mohammed Gazali;Asubonteng, Delali Pearl Afi;Yeboah, Cynthia Osei;Annor, Eugene Narkotey;Ankapong, Eunice Abena Kwartemaa;Boakye, Hosea
通过观察性研究，我们对非洲大陆卫生保健工作者 (HCW) 的冠状病毒 (COVID-19) 疫苗接受度和犹豫不决情况进行了调查。然而，目前还没有对非洲这些人口干部进行全面审查。因此，我们的目的是审查非洲医护人员不接受/犹豫不决的 COVID-19 疫苗的接受率和可能原因。我们于2020年1月至2021年9月检索了Medline/PubMed、Google Scholar和Africa Journal Online。使用适用于横断面研究的纽卡斯尔-渥太华质量评估工具来评估检索到的研究的质量。使用 DerSimonian 和 Laird 随机效应模型来汇总 COVID-19 疫苗接受率。进行了亚组和敏感性分析。还系统分析了 COVID-19 疫苗犹豫的原因。在 513 项初始记录中，发现二十一 (21) 项研究符合审查资格。预计汇总的 COVID-19 疫苗接受率为 46% [95% CI: 37%-54%]。北非的汇总估计 COVID-19 疫苗接受率为 37% [95% CI: 27%-47%]，中部非洲为 28% [95% CI: 20%-36%]，西非为 48% [CI: 38%-58%]，东非为 49% [95% CI: 30%-69%]，以及 90% [CI: 85%-96%] in Southern Africa.估计医护人员的汇总疫苗接受率为 48% [95% CI:38%-57%]，医疗保健学生的接受率为 34% [95% CI:29%-39%]。主要驱动因素和原因是疫苗的副作用、疫苗的安全性、有效性和有效性、临床试验持续时间短、COVID-19感染、信息有限和社会信任。数据显示，非洲各地医护人员对疫苗的接受度普遍较低。疫苗的副作用、疫苗的安全性、有效性和有效性、临床试验持续时间短、COVID-19感染、信息有限和社会信任是非洲对COVID-19犹豫不决的主要原因。非洲大陆必须尽快解决医护人员接受 COVID-19 疫苗的误解和障碍，以提高非洲的 COVID-19 疫苗接种率。
Coronavirus Disease (COVID-19) vaccine acceptance, and hesitancy amongst Health Care Workers (HCWs) on the African continent have been examined through observational studies. However, there are currently no comprehensive reviews among these cadre of population in Africa. Hence, we aimed to review the acceptance rate and possible reasons for COVID-19 vaccine non-acceptance/hesitancy amongst HCWs in Africa. We searched Medline/PubMed, Google Scholar, and Africa Journal Online from January, 2020 to September, 2021. The Newcastle-Ottawa Quality Assessment tool adapted for cross-sectional studies was used to assess the quality of the retrieved studies. DerSimonian and Laird random-effects model was used to pool the COVID-19 vaccine acceptance rate. Sub-group and sensitivity analyses were performed. Reasons for COVID-19 vaccine hesitancy were also systematically analyzed. Twenty-one (21) studies were found to be eligible for review out of the 513 initial records. The estimated pooled COVID-19 vaccine acceptance rate was 46% [95% CI: 37%-54%]. The pooled estimated COVID-19 vaccine acceptance rate was 37% [95% CI: 27%-47%] in North Africa, 28% [95% CI: 20%-36%] in Central Africa, 48% [CI: 38%-58%] in West Africa, 49% [95% CI: 30%-69%] in East Africa, and 90% [CI: 85%-96%] in Southern Africa. The estimated pooled vaccine acceptance was 48% [95% CI:38%-57%] for healthcare workers, and 34% [95% CI:29%-39%] for the healthcare students. Major drivers and reasons were the side effects of the vaccine, vaccine’s safety, efficacy and effectiveness, short duration of the clinical trials, COVID-19 infections, limited information, and social trust. The data revealed generally low acceptance of the vaccine amongst HCWs across Africa. The side effects of the vaccine, vaccine’s safety, efficacy and effectiveness, short duration of the clinical trials, COVID-19 infections, limited information, and social trust were the major reasons for COVID-19 hesitancy in Africa. The misconceptions and barriers to COVID-19 vaccine acceptance amongst HCWs must be addressed as soon as possible in the continent to boost COVID-19 vaccination rates in Africa.
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影响因子：
4.5
作者：
Kanyike AM;Olum R;Kajjimu J;Ojilong D;Akech GM;Nassozi DR;Agira D;Wamala NK;Asiimwe A;Matovu D;Nakimuli AB;Lyavala M;Kulwenza P;Kiwumulo J;Bongomin F
通讯作者：
Bongomin F
影响因子：
7.8
作者：
Gallè F;Sabella EA;Roma P;De Giglio O;Caggiano G;Tafuri S;Da Molin G;Ferracuti S;Montagna MT;Liguori G;Orsi GB;Napoli C
通讯作者：
Napoli C
影响因子：
--
作者：
Alle YF;Oumer KE
通讯作者：
Oumer KE
影响因子：
4.1
作者：
Agyekum, Martin Wiredu;Afrifa-Anane, Grace Frempong;Addo, Bright
通讯作者：
Addo, Bright
埃及的医疗保健工人中的Covid-19-19疫苗接种感和态度。
影响因子：
3.6
作者：
Fares S;Elmnyer MM;Mohamed SS;Elsayed R
通讯作者：
Elsayed R