Multifocal electroretinography as a function of age: the importance of normative values for older adults.

Multifocal electroretinography as a function of age: the importance of normative values for older adults.
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多焦视网膜电图作为年龄的函数:规范值对老年人的重要性。

DOI:
10.1167/iovs.02-0518
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发表时间:
2003
影响因子:
4.4
通讯作者:
Carr,RonaldE
Carr,RonaldE
中科院分区:
医学2区
文献类型:
--
作者:
Seiple,William;Vajaranant,ThasaratS;Szlyk,JanetP;Clemens,Colleen;Holopigian,Karen;Paliga,Jennifer;Badawi,David;Carr,RonaldE

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方法.多焦视网膜电图(mfERG)从62个正常视力的受试者,年龄从21岁到81岁。使用103个缩放六边形的刺激阵列来测量直径约为46的视网膜区域内的电信号。常用的mfERG方法被用来量化的反应:峰-峰振幅和隐式时间,标量积振幅,振幅和时间尺度来自Hood和Li的算法,发表于1997年。回归分析表明,幅度和时间措施与年龄呈显着的线性关系。峰-峰振幅的损失率为每十年10.5%,标积振幅为每十年11.7%,a标度为每十年9.5%。波幅降低率以中央3。年龄对内隐时间测量的影响较小。N1分量的时间损失率为每十年1.4%,P1分量和t尺度测量值均为每十年1.0%。使用预测区间范围,年龄计算时,50%的预期值将低于较低的95%预测区间带的年轻受试者。呈现与年龄相关的mfERG改变,以强调适当的规范性数据在mfERG解释中的重要性。
methods. Multifocal electroretinograms (mfERGs) were obtained from 62 normally sighted subjects ranging in age from 21 to 81 years. A stimulus array of 103 scaled hexagons was used to measure electrical signals within a retinal area approximately 46 in diameter. Commonly reported mfERG methods were used to quantify the responses: peak-to-peak amplitudes and implicit times, scalar product amplitude, and amplitude and time scales derived from the algorithm of Hood and Li, published in 1997.results. Regression analysis showed significant linear relationships of amplitude and timing measures with age. The rates of losses were 10.5% per decade for peak-to-peak amplitude, 11.7% per decade for scalar product amplitude, and 9.5% per decade for a-scale. The rate of amplitude reduction was highest in the central 3. Age had less influence on implicit time measures. The rates of timing losses were 1.4% per decade for the N1 component and 1.0% per decade for both the P1 component and the t-scale measure. Using predicted interval ranges, the age was calculated at which 50% of the expected values would fall below the lower 95% prediction interval band of younger subjects.conclusions. The age-associated mfERG alterations are presented to emphasize the importance of appropriate normative data in interpretation of mfERGs.
[衰老对多焦视网膜电图的影响]。
DOI: 10.1016/s0021-5155(00)00327-0
发表时间: 2000
期刊: Nippon Ganka Gakkai zasshi
影响因子: --
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T. Nabeshima
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DOI: --
发表时间: 1988
期刊: Clinical vision sciences
影响因子: --
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D. Pelli;J. Robson;A. Wilkins
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老化人类视网膜中视锥细胞内段的折射体。
DOI: --
发表时间: 1986
影响因子: 4.4
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Tucker,GS
通讯作者: Tucker,GS
黄斑视网膜电图作为受试者年龄的函数
DOI: 10.1007/bf00154734
发表时间: 1988
影响因子: 1.4
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