Impact of adverse childhood experiences on women's psychosocial and HIV-related outcomes and early child development in their offspring.
Impact of adverse childhood experiences on women's psychosocial and HIV-related outcomes and early child development in their offspring.
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DOI：
10.1080/17441692.2021.1986735
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发表时间：
2022-11
影响因子：
3.3
通讯作者：
Abrams EJ
中科院分区：
文献类型：
--
作者：
Brittain K;Zerbe A;Phillips TK;Gomba Y;Mellins CA;Myer L;Abrams EJ
不良童年经历 (ACE) 可能对成年结果和随后的后代发育产生关键影响，但很少有数据探讨 ACE 在儿童逆境和艾滋病毒负担较高的资源匮乏环境中的影响。在开普敦感染艾滋病毒的母亲中，我们研究了 ACE 对母亲社会心理和艾滋病毒相关结果以及 36-60 个月后代早期儿童发育的影响。世界卫生组织的不良童年经历国际调查问卷用于衡量母亲的 ACE 报告，年龄和阶段调查问卷用于筛查后代的发育迟缓。在 353 名女性（中位年龄：32 岁）中，84% 报告 ≥1 ACE。 ACE 报告的增加与抑郁症状、危险饮酒、亲密伴侣暴力以及自我报告的抗逆转录病毒治疗依从性不佳密切相关。这些协会是由更严重的童年经历驱动的，包括虐待、忽视和遭受集体暴力。在 255 名报告其孩子发育情况的女性中，母亲 ACE 与较差的社会情感发育有关。这些数据表明，童年逆境对母亲的结局及其孩子的社会情感发展具有长期影响，并指出可能作为筛查和干预目标的 ACE。
Adverse childhood experiences (ACEs) may have a critical influence on adult outcomes and subsequent offspring development, but few data have explored the effects of ACEs in low-resource settings where the burdens of childhood adversity and HIV are high. Among mothers living with HIV in Cape Town, we examined the effects of ACEs on maternal psychosocial and HIV-related outcomes, as well as early child development in their offspring aged 36–60 months. The World Health Organization’s Adverse Childhood Experiences International Questionnaire was used to measure maternal report of ACEs, and the Ages & Stages Questionnaire to screen for developmental delays in their offspring. Among 353 women (median age: 32 years), 84% reported ≥1 ACEs. Increased report of ACEs was strongly associated with depressive symptoms, hazardous alcohol use, intimate partner violence, and self-reported suboptimal adherence to antiretroviral therapy. These associations were driven by more severe childhood experiences, including abuse, neglect, and exposure to collective violence. Among 255 women who reported on their child’s development, maternal ACEs were associated with poorer socioemotional development. These data suggest that childhood adversity has long-term effects on maternal outcomes as well as their children’s socioemotional development, and point to ACEs that might be targeted for screening and intervention.
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DOI：
10.1016/s0140-6736(16)31389-7
发表时间：
2017-01-07
期刊：
Lancet (London, England)
影响因子：
--
作者：
Black MM;Walker SP;Fernald LCH;Andersen CT;DiGirolamo AM;Lu C;McCoy DC;Fink G;Shawar YR;Shiffman J;Devercelli AE;Wodon QT;Vargas-Barón E;Grantham-McGregor S;Lancet Early Childhood Development Series Steering Committee
通讯作者：
Lancet Early Childhood Development Series Steering Committee
影响因子：
1.9
作者：
Hsiao, C.;Richter, L.;Mabaso, M.
通讯作者：
Mabaso, M.
DOI：
10.1097/qad.0000000000001872
发表时间：
2018-08-24
期刊：
AIDS (London, England)
影响因子：
--
作者：
le Roux SM;Donald KA;Brittain K;Phillips TK;Zerbe A;Nguyen KK;Strandvik A;Kroon M;Abrams EJ;Myer L
通讯作者：
Myer L
影响因子：
1.8
作者：
Mogoba, Phepo;Gomba, Yolanda;Abrams, Elaine J.
通讯作者：
Abrams, Elaine J.
影响因子：
8
作者：
Folger, Alonzo T.;Eismann, Emily A.;Gillespie, Robert J.
通讯作者：
Gillespie, Robert J.