An efficient and accurate new method for locating the F3 position for prefrontal TMS applications.

An efficient and accurate new method for locating the F3 position for prefrontal TMS applications.
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DOI:
10.1016/j.brs.2008.09.006
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发表时间:
2009-01
期刊:
影响因子:
7.7
通讯作者:
George, Mark S.
George, Mark S.
中科院分区:
医学1区
文献类型:
--
作者:
Beam, William;Borckardt, Jeffrey J.;Reeves, Scott T.;George, Mark S.

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国际10-20系统是一种标准化放置脑电(EEG)电极的方法。10-20系统将外部颅骨位置与下面的皮质区域相关联。该系统通过使用周长的一定百分比和四个基本解剖标志之间的距离来说明患者颅骨尺寸的可变性。这种10-20系统最近已被用于经颅磁刺激(TMS)研究,用于定位特定的皮层区域。在治疗抑郁症(和某些类型的疼痛)时,TMS线圈的理想位置通常位于左背外侧前额叶皮层(DLPFC)上方,这与10-20系统给出的F3位置相对应。然而,对于对10-20系统没有什么经验的管理员来说,大量的测量和计算可能非常耗时。此外,随着更多的测量,人为错误的机会也更多。因此,我们开发了一种新的,更简单,更快的方法来找到F3位置,只需三次颅骨测量。在本文中,我们描述和说明了新的F3定位系统的应用,提供了用于计算F3位置的公式,并总结了10名健康成人的数据。在使用国际10-20系统和这种新方法后,新方法似乎足够准确;然而,未来的调查可能需要对该方法的实用性和潜在局限性进行更多的深入分析。该系统需要更少的时间和训练来找到前额线圈放置的最佳位置,并且与10-20 EEG系统相比节省了相当多的时间。
The International 10–20 system is a method for standardized placement of electroencephalogram (EEG) electrodes. The 10–20 system correlates external skull locations with the underlying cortical areas. This system accounts for variability in patient skull size by using certain percentages of the circumference and distances between four basic anatomical landmarks. This 10–20 system has recently been used in transcranial magnetic stimulation (TMS) research for locating specific cortical areas. In the treatment of depression (and some types of pain), the desired placement of the TMS coil is often above the left dorsalateral prefrontal cortex (DLPFC) which corresponds to the F3 location given by the 10–20 system. However, for an administrator with little experience with the 10–20 system, the numerous measurements and calculations can be excessively time-consuming. Additionally, with more measurements comes more opportunity for human error. For this reason we have developed a new, simpler and faster way to find the F3 position using only three skull measurements. In this paper, we describe and illustrate the application of the new F3 location system, provide the formulas used in the calculation of the F3 position, and summarize data from 10 healthy adults. After using both the International 10–20 system and this new method, it appears that the new method is sufficiently accurate; however, future investigations may be warranted to conduct more in dept analyses of the method's utility and potential limitations. This system requires less time and training to find the optimal position for prefrontal coil placement and it saves considerable time compared to the 10–20 EEG system.
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