Dynamic cardiac MRI with high spatiotemporal resolution using accelerated spiral-out and spiral-in/out bSSFP pulse sequences at 1.5 T.

Dynamic cardiac MRI with high spatiotemporal resolution using accelerated spiral-out and spiral-in/out bSSFP pulse sequences at 1.5 T.
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DOI:
10.1007/s10334-023-01116-9
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发表时间:
2023-12
期刊:
Magma (New York, N.Y.)
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其他
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为了开发两种基于螺旋的bSSFP脉冲序列结合L + S重建用于1.5T加速无门控自由呼吸动态心脏成像,通过仿真和在体心脏动态成像研究,对微小黄金角度旋转螺旋输出和螺旋输入/输出bSSFP序列结合视角共享(VS)、压缩传感(CS)和低阶加稀疏(L + S)重建的心脏动态成像进行了评估和比较。然后,根据标准电影在定量图像评估和定性质量评级方面对所提出的方法进行了验证。在三种方法中,L + S方法得到的残余伪影最少,图像清晰度最好。两种螺旋电影技术均显示临床诊断图像(评分 > 3)。与标准电影相比,螺旋电影技术在整体图像质量和边缘清晰度方面有显著差异,而螺旋电影技术在图像对比度方面有显著差异,而螺旋电影在图像对比度方面没有显著差异。螺旋输出电影(− 1.6~3.1%)和螺旋输入/输出电影(− 1.5~2.8%)的左心室射血分数与标准电影有很好的一致性。与需要心电门控和屏气的耗时的标准电影(~ 5分钟)相比,建议的螺旋bSSFP序列可以在相似的空间(1.5 × 1.5 × 8 mm~3)和时间分辨率(36 Ms)下实现无门控、自由呼吸的心脏电影,覆盖整个心脏(10-15个切片)45°S,这表明临床上有潜力改善患者的舒适度,或对心律失常或无法屏息的患者进行成像。网上版载有补充材料,可在10.1007/s10334-023-01116-9查阅。
To develop two spiral-based bSSFP pulse sequences combined with L + S reconstruction for accelerated ungated, free-breathing dynamic cardiac imaging at 1.5 T. Tiny golden angle rotated spiral-out and spiral-in/out bSSFP sequences combined with view-sharing (VS), compressed sensing (CS), and low-rank plus sparse (L + S) reconstruction were evaluated and compared via simulation and in vivo dynamic cardiac imaging studies. The proposed methods were then validated against the standard cine, in terms of quantitative image assessment and qualitative quality rating. The L + S method yielded the least residual artifacts and the best image sharpness among the three methods. Both spiral cine techniques showed clinically diagnostic images (score > 3). Compared to standard cine, there were significant differences in global image quality and edge sharpness for spiral cine techniques, while there was significant difference in image contrast for the spiral-out cine but no significant difference for the spiral-in/out cine. There was good agreement in left ventricular ejection fraction for both the spiral-out cine (− 1.6 3.1%) and spiral-in/out cine (− 1.5 2.8%) against standard cine. Compared to the time-consuming standard cine (~ 5 min) which requires ECG-gating and breath-holds, the proposed spiral bSSFP sequences achieved ungated, free-breathing cardiac movies at a similar spatial (1.5 × 1.5 × 8 mm3) and temporal resolution (36 ms) per slice for whole heart coverage (10–15 slices) within 45 s, suggesting the clinical potential for improved patient comfort or for imaging patients with arrhythmias or who cannot hold their breath. The online version contains supplementary material available at 10.1007/s10334-023-01116-9.
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