Exercise as a therapeutic modality for the prevention and treatment of depression.
Exercise as a therapeutic modality for the prevention and treatment of depression.
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DOI：
10.1016/j.pcad.2023.02.008
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发表时间：
2023-03
影响因子：
9.1
通讯作者：
Rozanski, Alan
中科院分区：
文献类型：
--
作者：
Blumenthal, James A.;Rozanski, Alan
虽然保持积极的生活方式和定期锻炼可以促进心血管（CV）健康，但越来越多的证据表明，这些生活方式行为也可以促进心理健康和幸福。这导致了一项研究，以确定运动是否可以作为重度抑郁症（MDD）的潜在治疗方式，这是全球精神健康损害和整体残疾的主要原因。支持这种用途的最有力证据来自越来越多的随机临床试验（RCT），这些试验将运动与健康成人和各种临床人群的常规护理，安慰剂对照或既定疗法进行了比较。相对大量的随机对照试验导致了大量的综述和荟萃分析，这些综述和荟萃分析通常一致地表明，运动可以改善抑郁症状，提高自尊，并提高生活质量的各个方面。总之，这些数据表明，运动应被视为改善心血管健康和心理健康的治疗方式。新出现的证据也导致了一个新的“生活方式精神病学”亚专业的提出，它促进了运动作为MDD患者的一种预防性治疗。事实上，一些医疗组织现在已经认可基于生活方式的方法作为抑郁症管理的基础方面，并将运动作为MDD的治疗选择。本文综述了这一领域的研究，并为临床实践中使用运动提供了切实可行的建议。
While maintaining an active lifestyle and engaging in regular exercise are known to promote cardiovascular (CV) health, increasing evidence has emerged to indicate that these lifestyle behaviors also can promote psychological health and well-being. This has led to research to determine if exercise can serve as a potential therapeutic modality for major depressive disorder (MDD), which is a leading cause of mental-health impairment and overall disability worldwide. The strongest evidence to support this use comes from an increasing number of randomized clinical trials (RCTs) that have compared exercise to usual care, placebo controls, or established therapies in healthy adults and in various clinical populations. The relatively large number of RCTs has led to numerous reviews and meta-analyses, which generally have been concordant in indicating that exercise ameliorates depressive symptoms, improves self-esteem, and enhances various aspects of quality of life. Together, these data indicate that exercise should be considered as a therapeutic modality for improving CV health and psychological well-being. The emerging evidence also has led to a new proposed subspecialty of “lifestyle psychiatry”, which promotes the use of exercise as an adjunctive treatment for patients with MDD. Indeed, some medical organizations have now endorsed lifestyle-based approaches as foundational aspects of depression management, with adoption of exercise as a treatment option for MDD. This review summarizes research in the area and provides practical suggestions for the use of exercise in clinical practice.
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影响因子：
37.8
作者：
Blumenthal JA;Sherwood A;Smith PJ;Watkins L;Mabe S;Kraus WE;Ingle K;Miller P;Hinderliter A
通讯作者：
Hinderliter A
影响因子：
25.8
作者：
Blumenthal, James A.;Smith, Patrick J.;Sherwood, Andrew
通讯作者：
Sherwood, Andrew
冠状动脉疾病患者的抑郁症状的运动和药理治疗：乐观的结果（了解运动和抗抑郁治疗的预后益处）研究。
影响因子：
24
作者：
Blumenthal, James A.;Sherwood, Andrew;Babyak, Michael A.;Watkins, Lana L.;Smith, Patrick J.;Hoffman, Benson M.;O'Hayer, C. Virginia F.;Mabe, Stephanie;Johnson, Julie;Doraiswamy, P. Murali;Jiang, Wei;Schocken, Douglas D.;Hinderliter, Alan L.
通讯作者：
Hinderliter, Alan L.
影响因子：
3.3
作者：
Babyak, M;Blumenthal, JA;Krishnan, KR
通讯作者：
Krishnan, KR
影响因子：
5
作者：
CAMACHO, TC;ROBERTS, RE;COHEN, RD
通讯作者：
COHEN, RD