Comparative metabolomics analysis of milk components between Italian Mediterranean buffaloes and Chinese Holstein cows based on LC-MS/MS technology.
Comparative metabolomics analysis of milk components between Italian Mediterranean buffaloes and Chinese Holstein cows based on LC-MS/MS technology.
复制标题
基于LC-MS/MS技术的意大利地中海水牛和中国荷斯坦奶牛乳成分比较代谢组学分析
DOI：
10.1371/journal.pone.0262878
复制
发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Shi D
中科院分区：
文献类型：
--
作者：
Yuan X;Shi W;Jiang J;Li Z;Fu P;Yang C;Rehman SU;Pauciullo A;Liu Q;Shi D
就脂肪、蛋白质和总固体而言，水牛奶和牛奶的组成非常不同。为了更好地了解这种差异，本研究以意大利地中海水牛和中国荷斯坦奶牛为研究对象，采用LC-MS/MS联用技术对其乳代谢特征和代谢产物特性进行了研究。共鉴定出23种差异代谢物，其中15种在意大利地中海水牛中上调，8种在意大利地中海水牛中下调。代谢途径分析表明，4种代谢产物(胆碱、乙酰胆碱、烟酰胺和尿酸)显著富含甘油磷脂代谢、烟酸和烟酰胺代谢、甘氨酸、丝氨酸和苏氨酸代谢以及嘌呤代谢。这些结果为深入了解导致意大利地中海水牛和中国荷斯坦奶牛奶性能差异的潜在代谢机制提供了进一步的见解。研究结果将为奶业的改进提供新的工具，为奶业的发展提供新的方向。
Buffalo and cow milk have a very different composition in terms of fat, protein, and total solids. For a better knowledge of such a difference, the milk metabolic profiles and characteristics of metabolites was investigated in Italian Mediterranean buffaloes and Chinese Holstein cows were investigated by liquid chromatography tandem-mass spectrometry (LC-MS/MS) in this study. Totally, 23 differential metabolites were identified to be significantly different in the milk from the two species of which 15 were up-regulated and 8 down-regulated in Italian Mediterranean buffaloes. Metabolic pathway analysis revealed that 4 metabolites (choline, acetylcholine, nicotinamide and uric acid) were significantly enriched in glycerophospholipid metabolism, nicotinate and nicotinamide metabolism, glycine, serine and threonine metabolism, as well as purine metabolism. The results provided further insights for a deep understanding of the potential metabolic mechanisms responsible for the different performance of Italian Mediterranean buffaloes’ and Chinese Holstein cows’ milk. The findings will offer new tools for the improvement and novel directions for the development of dairy industry.
登录
查看更多内容
影响因子：
3.5
作者：
Melzer, N.;Wittenburg, D.;Repsilber, D.
通讯作者：
Repsilber, D.
水牛乳中脂肪酸生物合成和硬脂酰辅酶A去饱和酶1 (SCD1)的转录调控
影响因子：
2.9
作者：
Li, Zhipeng;Lu, Suyu;Liu, Qingyou
通讯作者：
Liu, Qingyou
影响因子：
4.5
作者：
Khan, Imran Taj;Nadeem, Muhammad;Khalique, Anjum
通讯作者：
Khalique, Anjum
影响因子：
4.5
作者：
Batool M;Nadeem M;Imran M;Khan IT;Bhatti JA;Ayaz M
通讯作者：
Ayaz M
影响因子：
3.5
作者：
Klein, M. S.;Almstetter, M. F.;Gronwald, W.
通讯作者：
Gronwald, W.