The Impact of Tobacco Use on COVID-19 Outcomes: A Systematic Review.

The Impact of Tobacco Use on COVID-19 Outcomes: A Systematic Review.
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DOI:
10.1155/2022/5474397
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发表时间:
2022
影响因子:
0.9
通讯作者:
Berg CJ
Berg CJ
中科院分区:
其他
文献类型:
--
作者:
Baker J;Krishnan N;Abroms LC;Berg CJ

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吸烟增加了许多疾病的风险,包括呼吸道疾病。我们检查了文献,以确定烟草使用史是否会增加COVID-19患者不良结局的风险。 我们使用COVID-19和烟草相关术语对PubMed、LitCovid、Scopus和Europe PMC(预印本)进行了系统检索。我们纳入了对实验室确诊的COVID-19感染的人类受试者的研究,这些研究将烟草使用史作为一种暴露,并使用了多变量分析。数据收集于2020年3月31日至2021年2月20日之间。结果包括死亡率、住院、ICU入院、机械通气和疾病严重程度。 在纳入的39项研究(33项同行评审,6项预印本)中,评估的最常见结局是死亡率(n = 32)。这些研究中的大多数(17/32)发现烟草使用增加了风险,一项发现降低了风险,14项发现没有关联。在10项研究中,7项研究中的烟草使用与住院风险增加相关,9项研究中的6项研究中的ICU入院风险增加,6项研究中的2项研究中的机械通气风险增加,9项研究中的3项研究中的疾病严重程度增加。一项研究发现,吸烟史增加了COVID-19患者发生肺栓塞的风险。研究发现,烟草使用会增加与糖尿病(n = 1)、癌症(n = 2)和慢性肝病(n = 1)相关的风险。 有强有力的证据表明,烟草使用增加了COVID-19患者的死亡率和疾病严重程度/进展的风险。大流行期间的公共卫生工作应鼓励烟草使用者戒烟并尽早寻求护理,并在有烟草使用史的人中促进疫苗接种和其他预防行为。
Tobacco use increases risks for numerous diseases, including respiratory illnesses. We examined the literature to determine whether a history of tobacco use increases risks for adverse outcomes among COVID-19 patients. We conducted a systematic search of PubMed, LitCovid, Scopus, and Europe PMC (for preprints) using COVID-19 and tobacco-related terms. We included studies of human subjects with lab-confirmed COVID-19 infections that examined tobacco use history as an exposure and used multivariable analyses. The data was collected between March 31st, 2020, and February 20th, 2021. Outcomes included mortality, hospitalization, ICU admission, mechanical ventilation, and illness severity. Among the 39 studies (33 peer-reviewed, 6 preprints) included, the most common outcome assessed was mortality (n = 32). The majority of these studies (17/32) found that tobacco use increased risk, one found decreased risk, and 14 found no association. Tobacco use was associated with increased risk of hospitalization in 7 of 10 studies, ICU admission in 6 of 9 studies, mechanical ventilation in 2 of 6 studies, and illness severity in 3 of 9 studies. One study found that tobacco use history increased risk of pulmonary embolism in COVID-19 patients. Tobacco use was found to compound risks associated with diabetes (n = 1), cancer (n = 2), and chronic liver disease (n = 1). There is strong evidence that tobacco use increases risks of mortality and disease severity/progression among COVID-19 patients. Public health efforts during the pandemic should encourage tobacco users to quit use and seek care early and promote vaccination and other preventive behaviors among those with a history of tobacco use.
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