An artery-specific fluorescent dye for studying neurovascular coupling.
An artery-specific fluorescent dye for studying neurovascular coupling.
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DOI:
10.1038/nmeth.1857
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发表时间:
2012-01-22
期刊:
影响因子:
48
通讯作者:
Kara, Prakash
中科院分区:
文献类型:
--
作者:
Shen, Zhiming;Lu, Zhongyang;Chhatbar, Pratik Y.;O'Herron, Philip;Kara, Prakash
We demonstrate that Alexa Fluor 633 hydrazide (Alexa Fluor 633) selectively labels neocortical arteries and arterioles by binding to elastin fibers. We measured sensory stimulus–evoked arteriole dilation dynamics in mouse, rat and cat visual cortex using Alexa Fluor 633 together with neuronal activity using calcium indicators or blood flow using fluorescein dextran. Arteriole dilation decreased fluorescence recorded from immediately underlying neurons, representing a potential artifact during neuronal functional imaging experiments.
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影响因子:
1.2
作者:
Drew PJ;Blinder P;Cauwenberghs G;Shih AY;Kleinfeld D
通讯作者:
Kleinfeld D
影响因子:
48
作者:
Drew, Patrick J.;Shih, Andy Y.;Driscoll, Jonathan D.;Knutsen, Per Magne;Blinder, Pablo;Davalos, Dimitrios;Akassoglou, Katerina;Tsai, Philbert S.;Kleinfeld, David
通讯作者:
Kleinfeld, David
DOI:
10.3389/fnene.2011.00001
发表时间:
2011-01-01
期刊:
Frontiers in neuroenergetics
影响因子:
--
作者:
Kleinfeld, David;Blinder, Pablo;Shih, Andy Y
通讯作者:
Shih, Andy Y
影响因子:
64.8
作者:
Ohki, Kenichi;Chung, Sooyoung;Reid, R. Clay
通讯作者:
Reid, R. Clay
DOI:
10.1073/pnas.1100428108
发表时间:
2011-05-17
影响因子:
11.1
作者:
Drew, Patrick J.;Shih, Andy Y.;Kleinfeld, David
通讯作者:
Kleinfeld, David