Preliminary examination of the comorbidity of anxiety and depression in Parkinson's disease.

Preliminary examination of the comorbidity of anxiety and depression in Parkinson's disease.
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帕金森病焦虑抑郁共病的初步检查。

DOI:
10.1176/jnp.4.3.257
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发表时间:
1992
期刊:
The Journal of neuropsychiatry and clinical neurosciences
影响因子:
--
通讯作者:
Como,P
Como,P
中科院分区:
--
文献类型:
--
作者:
Henderson,R;Kurlan,R;Kersun,JM;Como,P

文献摘要

参考文献

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严重的焦虑和抑郁可能代表了帕金森氏病(PD)中一种特殊的抑郁亚型。为了确定这种症状复合体的患病率,我们对164名PD患者和150名年龄匹配的健康配偶对照组进行了自我报告调查和标准化心理测试,以衡量焦虑和抑郁。抑郁和恐慌/焦虑的报告最好地区分了这两个人群(38%对8%)。抑郁和焦虑与帕金森病的临床特征高度相关。我们的发现表明,在临床上,抑郁和焦虑水平可能经常共存于帕金森病患者。帕金森病的特殊神经病理可能是这种行为障碍的易感因素。
Significant anxiety in combination with depression may represent a specific depressive subtype in Parkinson's disease (PD). To ascertain the prevalence of this symptom complex, we administered a self-report survey and standardized psychological tests that measure anxiety and depression to 164 PD patients and 150 age-matched healthy spouse control subjects. The reporting of depression in combination with panic/anxiety best differentiated the two populations (38% vs. 8%). Depression and anxiety were highly correlated in relationship to clinical features of PD. Our findings suggest that clinically significant levels of depression and anxiety may frequently coexist in PD. The specific neuropathology of PD may predispose to this pattern of behavioral disturbance.
DOI: --
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