A Non-parametric Approach to Detect Epileptogenic Lesions using Restricted Boltzmann Machines
A Non-parametric Approach to Detect Epileptogenic Lesions using Restricted Boltzmann Machines
复制标题
使用受限玻尔兹曼机检测致癫痫病变的非参数方法
DOI:
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复制
发表时间:
2016
期刊:
影响因子:
--
通讯作者:
O. Devinsky
中科院分区:
文献类型:
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作者:
Yijun Zhao;Bilal Ahmed;T. Thesen;K. Blackmon;Jennifer G. Dy;C. Brodley;R. Kuzniecky;O. Devinsky
Visual detection of lesional areas on a cortical surface is critical in rendering a successful surgical operation for Treatment Resistant Epilepsy (TRE) patients. Unfortunately, 45% of Focal Cortical Dysplasia (FCD, the most common kind of TRE) patients have no visual abnormalities in their brains' 3D-MRI images. We collaborate with doctors from NYU Langone's Comprehensive Epilepsy Center and apply machine learning methodologies to identify the resective zones for these {MRI-negative} FCD patients. Our task is particularly challenging because MRI images can only provide a limited number of features. Furthermore, data from different patients often exhibit inter-patient variabilities due to age, gender, left/right handedness, etc. In this paper, we introduce a new approach which combines the restricted Boltzmann machines and a Bayesian non-parametric mixture model to address these issues. We demonstrate the efficacy of our model by applying it to a retrospective dataset of MRI-negative FCD patients who are seizure free after surgery.
影响因子:
3.7
作者:
Salat, DH;Buckner, RL;Fischl, B
通讯作者:
Fischl, B
DOI:
10.1073/pnas.200033797
发表时间:
2000-09-26
影响因子:
11.1
作者:
Fischl, B;Dale, AM
通讯作者:
Dale, AM