Induction of systemic and local basophil and eosinophil responses in guinea pigs by the feeding of the tsetse fly Glossina morsitans.
Induction of systemic and local basophil and eosinophil responses in guinea pigs by the feeding of the tsetse fly Glossina morsitans.
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通过喂养采采蝇 Glossina morsitans 诱导豚鼠全身和局部嗜碱性粒细胞和嗜酸性粒细胞反应。
DOI：
10.1016/0304-4017(85)90025-1
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发表时间：
1985
影响因子：
2.6
通讯作者：
Cipriano,DM
中科院分区：
文献类型：
--
作者：
Brown,SJ;Cipriano,DM
Guinea pigs infested withGlossina morsitansweekly for 5 weeks exhibited marked peripheral blood basophil and eosinophil responses to each infestation, with a dominant cutaneous basophil response to challenge infestation.G. morsitansfeeding was completed within 3–10 min, depending upon prior exposure, and flies were reluctant to feed and probed longer on hyperexposed animals.Blood basophil responses exhibited the greatest increases over controls (up to 12-fold) compared to eosinophils (up to 3-fold). After the first and third infestations, both basophil and eosinophil levels increased, whereas after the second and fourth infestations both cell types declined. Greatest blood basophil responses developed after the first infestation with levels ranging from 0 to 14 ± 9 cells/mm3in infested animals to 0 and 2 ± 2 cells/mm3in uninfested controls. Eosinophilia increased with each infestation where levels ranged from 57 ± 23 cells/mm3after the first tsetse feeding to 110 ± 20 cells/mm3after the fourth infestation; compared to 11 ± 11 to 50 ± 12 cells/mm3in uninfested controls.Fly-feeding sites were marked by hemorrhages, and probing behavior resulted in a line of small hemorrhages when the underside of the skin was examined. Histologically,G. morsitansfeeding sites in naive guinea pigs 24 h post-infestation were dominated by mononuclear cells (93% of the infiltrate) with a weak granulocyte component, of which eosinophils were dominant (1.3%). Tsetse feeding sites in guinea pigs exposed 3 times previously were again dominated by mononuclear cells (57% of the infiltrate), but granulocytes comprised a significant part of the response (43% of the infiltrate) where basophils were dominant (25%).
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影响因子：
15.3
作者：
Grove, D I;Mahmoud, A A;Warren, K S
通讯作者：
Warren, K S
影响因子：
1.1
作者：
Bagnall, B. G.;Doube, B. M.
通讯作者：
Doube, B. M.
用于维持未感染的实验室饲养采采蝇（Glossina morsitans morsitans Westwood）的兔子的血清学反应（双翅目：舌蝇科）。
影响因子：
1.4
作者：
K. Parker
通讯作者：
K. Parker
特异性抗体：一种潜在的杀虫剂。
影响因子：
56.9
作者：
G. Nogge;M. Giannetti
通讯作者：
M. Giannetti
影响因子：
64.8
作者：
J. Allen;S. Humphreys
通讯作者：
S. Humphreys