Design of DNA origami
Design of DNA origami
复制标题
DNA折纸设计
DOI:
--
复制
发表时间:
2005
期刊:
影响因子:
--
通讯作者:
P. Rothemund
中科院分区:
文献类型:
--
作者:
P. Rothemund
The generation of arbitrary patterns and shapes at very small scales is at the heart of our effort to miniaturize circuits and is fundamental to the development of nanotechnology. Here I review a recently developed method for folding long single strands of DNA into arbitrary two-dimensional shapes using a raster fill technique - 'scaffolded DNA origami'. Shapes up to 100 nanometers in diameter can be approximated with a resolution of 6 nanometers and decorated with patterns of roughly 200 binary pixels at the same resolution. Experimentally verified by the creation of a dozen shapes and patterns, the method is easy, high yield, and lends itself well to automated design and manufacture. So far, CAD tools for scaffolded DNA origami are simple, require hand-design of the folding path, and are restricted to two dimensional designs. If the method gains wide acceptance, better CAD tools will be required.
影响因子:
2.9
作者:
FU, TJ;SEEMAN, NC
通讯作者:
SEEMAN, NC
DOI:
10.1080/07391102.1990.10507829
发表时间:
1990-12-01
影响因子:
4.4
作者:
SEEMAN, NC
通讯作者:
SEEMAN, NC
影响因子:
2
作者:
SEEMAN, NC
通讯作者:
SEEMAN, NC