The role of future-oriented affect in engagement with genomic testing results.

The role of future-oriented affect in engagement with genomic testing results.
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DOI:
10.1007/s10865-021-00253-7
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发表时间:
2022-03
影响因子:
3.1
通讯作者:
Ferrer RA
Ferrer RA
中科院分区:
心理学3区
文献类型:
--
作者:
Gillman AS;Iles IA;Klein WMP;Biesecker BB;Lewis KL;Biesecker LG;Ferrer RA

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面向未来的情绪,如预期影响(即,关于潜在的未来结果所经历的当前影响)和预期影响(即,对未来潜在影响的预期),与健康决策唯一相关(例如,选择接收基因组测试的结果)。这项研究调查了负面预期和预期情绪随着时间的推移预测健康决策的程度,以及这些情绪是否预测对预期信息的社会,情绪和行为反应(例如,基因组检测结果)。本研究纳入了基因组测序队列中选择接受基因组测序(携带者)结果的461名参与者(M年龄=63.9,SD=5.61,46%女性)。在基线时评估测序结果的预期和预期影响。对测序结果的心理和行为反应,包括参与者报告的焦虑,决策冲突和对测序结果的困扰,他们是否与家人分享结果,以及他们将来继续学习结果的意图,在收到结果后立即收集,一个月和/或六个月。基线时更多的负面预期和预期影响与未来继续学习结果的意图较低以及收到结果后多个时间点的焦虑和不确定性水平较高显著且独立相关。预期的负面影响也与更大的决策冲突,预期的负面影响也与收到结果后更大的痛苦。未来导向的情绪可能在随着时间的推移而展开的决策中发挥重要作用,对基因组测试,行为医学和健康决策具有广泛的影响。
Future-oriented emotions such as anticipatory affect (i.e., current affect experienced regarding a potential future outcome) and anticipated affect (i.e., expectations about potential future affect), are uniquely associated with health decision-making (e.g., electing to receive results of genomic testing). This study investigated the degree to which negative anticipated and anticipatory emotions predict health decision making over time, and whether such emotions predict social, emotional, and behavioral responses to anticipated information (e.g., genomic testing results). 461 participants (M age=63.9, SD=5.61, 46% female) in a genomic sequencing cohort who elected to receive genomic sequencing (carrier) results were included in the current study. Anticipated and anticipatory affect about sequencing results were assessed at baseline. Psychological and behavioral responses to sequencing results, including participants’ reported anxiety, decisional conflict, and distress about sequencing results, whether they shared results with family members, and their intentions to continue learning results in the future, were collected immediately, one month, and/or six months after receiving results. More negative anticipated and anticipatory affect at baseline was significantly and independently associated with lower intentions to continue learning results in the future, as well as higher levels of anxiety and uncertainty at multiple time points after receiving results. Anticipated negative affect was also associated with greater decisional conflict, and anticipatory negative affect was also associated with greater distress after receiving results. Future-oriented emotions may play an important role in decisions that unfold over time, with implications for genomic testing, behavioral medicine, and health decision-making broadly.
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