US national treatment admissions with opioids and benzodiazepines.

US national treatment admissions with opioids and benzodiazepines.
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美国国家治疗阿片类药物和苯二氮卓类药物的入院。

DOI:
10.1111/dar.13129
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发表时间:
2020-11
影响因子:
3.8
通讯作者:
Greenwald, Mark K.
Greenwald, Mark K.
中科院分区:
医学3区
文献类型:
--
作者:
Arfken, Cynthia L.;Owens, Darlene D.;Greenwald, Mark K.

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在美国,阿片类药物和苯二氮卓类药物(O/BZD)越来越多地与药物过量死亡有关。扩大治疗能力可能会减少这些死亡人数。需要了解同时发生的O/BZD入院与阿片类药物(阿片类药物)入院的比较,以计划这一扩大。对2011-2017年间美国专科机构的治疗入院人数进行了趋势分析,并对2017年的群体差异进行了分析。由于2017年有190万入院,O/BZD和阿片类药物入院之间的比较总结为效果大小。另外的分析比较了管理预先编码的“其他阿片剂和合成物”与其他鸦片和合成物/苯二氮卓类药物的入院情况,以控制毒品来源可能的相似性。探讨原发药物入院时O/BZD患者的差异。尽管阿片类药物的入院人数随着时间的推移显示出稳步增长(25.9%至38.2%),但O/BZD的入院人数在2017年之前一直呈上升趋势(3.2%至4.0%)。2017年,在小组比较或O/BZD入院人数中,没有任何因素达到中等效果大小(≥0.2%)。在O/BZD和阿片类药物入院的患者中,70%的人自我报告了海洛因。与阿片类药物入院相比,在常规收集的O/BZD数据上,没有发现有意义的美国全国差异,包括仅使用其他阿片类药物和合成药物的亚组。努力将现有的阿片类药物治疗扩大到专门治疗中,可能有助于减少阿片类药物和O/BZD的死亡。然而,这项分析无法解决治疗方法的改变是否会改善结果。访问数/每百万人:Reach for[Arfken CL,Owens D.阿片类药物和苯二氮卓类药物的美国国民待遇准入。毒品酒精2020版]
Opioids and benzodiazepines (O/BZD) are increasingly involved in drug overdose deaths in the USA. Expanding treatment capacity may reduce these deaths. Knowledge about co-occurring O/BZD admissions compared to opioid admissions (opioid) is needed to plan this expansion. US treatment admissions to specialty facilities for 2011–2017 were analysed for trends and 2017 for group differences. Due to 1.9 million admissions in 2017, comparisons between O/BZD and opioid admissions were summarised as effect sizes. Additional analysis compared the administratively pre-coded category ‘other opiates and synthetics’ to other opiates and synthetics/benzodiazepines admissions to control for possible similarity in drug source. Differences within O/BZD admissions by primary drug were explored. Although opioid admissions showed a steady increase over time (25.9% to 38.2%), O/BZD admissions showed increases until decline in 2017 (3.2% to 4.0%). In 2017 no factor reached moderate effect size (≥0.2) in group comparisons or within the O/BZD admissions. Heroin was self-reported in 70% of both O/BZD and opioid admissions. No meaningful US national differences on data routinely collected were found for O/BZD compared to opioid admissions including the subgroup with other opiates and synthetics only. Efforts to expand existing opioid treatment in specialty treatments may help reduce opioid and O/BZD deaths. However, the analysis could not address whether changes in treatment would improve outcomes. [Arfken CL, Owens DD, Greenwald MK. US national treatment admissions with opioids and benzodiazepines. Drug Alcohol Rev 2020]
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