A viewpoint on change point modeling for cognitive aging research: Moving from description to intervention and practice.

A viewpoint on change point modeling for cognitive aging research: Moving from description to intervention and practice.
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DOI:
10.1016/j.arr.2019.101003
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发表时间:
2020-03
影响因子:
13.1
通讯作者:
Ross LA
Ross LA
中科院分区:
医学1区
文献类型:
--
作者:
Sprague BN;Freed SA;Phillips CB;Ross LA

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实足年龄是一种常用的时间度量,但在老年期可能有更相关的时间度量。变化点模型是认知衰老研究中越来越常见的一种分析方法,但在应用研究中的应用有限。在此,我们提出了一种新的认知训练模型的应用。变化点模型具有评估干预结果的潜力,例如在事件发生后降低发病率或减少下降(例如,痴呆诊断后减少认知能力下降),以及不同干预剂量(例如,初始训练与强化训练)的结果轨迹变化。通过变化点模型,我们可以更好地理解干预如何影响认知衰老轨迹。
Chronological age is a commonly-used time metric, but there may be more relevant time measures in older adulthood. This paper reviews change point modeling, a type of analysis increasingly common in cognitive aging research but with limited application in applied research. Here, we propose a new application of such models for cognitive training studies. Change point models have the potential to assess intervention outcomes such as compression of morbidity or reduced decline after an event (e.g., reduced cognitive decline after a dementia diagnosis) as well as changes in outcome trajectories across different intervention dosages (e.g., initial vs. booster training). Through change point modeling, we can better understand how interventions impact cognitive aging trajectories.
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