Efficacy of Olyset® Plus, a new long-lasting insecticidal net incorporating permethrin and piperonyl-butoxide against multi-resistant malaria vectors [corrected].
Efficacy of Olyset® Plus, a new long-lasting insecticidal net incorporating permethrin and piperonyl-butoxide against multi-resistant malaria vectors [corrected].
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DOI：
10.1371/journal.pone.0075134
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Corbel V
中科院分区：
文献类型：
--
作者：
Pennetier C;Bouraima A;Chandre F;Piameu M;Etang J;Rossignol M;Sidick I;Zogo B;Lacroix MN;Yadav R;Pigeon O;Corbel V
由于拟除虫菊酯在全球疟疾媒介中的抗药性迅速扩大，制造商正在开发新的媒介控制工具，包括含有至少两种不同作用模式的有效成分的杀虫剂混合物，作为抗药性管理的一部分。Olyset®Plus是一种新型长效杀虫蚊帐(LLIN)，在其纤维中加入氯菊酯和增效剂胡椒基丁醚(PBO)，以中和基于代谢的蚊虫拟除虫菊酯抗性。在这项研究中，我们在实验室和现场评估了Olyset®Plus对敏感和多重抗药性疟疾媒介的效果，并与Olyset Net进行了比较，Olyset Net是一种在聚乙烯网中加入的氯菊酯。在实验室中，Olyset®Plus对冈比亚按蚊敏感品系的效果优于Olyset®Net，再生时间为2天，这是因为新的掺入技术提高了氯菊酯的出血率。与Olyset®Net相比，它对多种抗药性人群的抗药性也更好。冈比亚在西非的试验性小屋试验中。此外，本研究表明，在蚊帐中加入增效剂PBO和拟除虫菊酯杀虫剂是有益的。这些结果需要在大规模实地试验中进一步验证，以评估这一疟疾病媒控制新工具的持久性和可接受性。
Due to the rapid extension of pyrethroid resistance in malaria vectors worldwide, manufacturers are developing new vector control tools including insecticide mixtures containing at least two active ingredients with different mode of action as part of insecticide resistance management. Olyset® Plus is a new long-lasting insecticidal net (LLIN) incorporating permethrin and a synergist, piperonyl butoxide (PBO), into its fibres in order to counteract metabolic-based pyrethroid resistance of mosquitoes. In this study, we evaluated the efficacy of Olyset® Plus both in laboratory and field against susceptible and multi-resistant malaria vectors and compared with Olyset Net, which is a permethrin incorporated into polyethylene net. In laboratory, Olyset® Plus performed better than Olyset® Net against susceptible Anopheles gambiae strain with a 2-day regeneration time owing to an improved permethrin bleeding rate with the new incorporation technology. It also performed better than Olyset® Net against multiple resistant populations of An. gambiae in experimental hut trials in West Africa. Moreover, the present study showed evidence for a benefit of incorporating a synergist, PBO, with a pyrethroid insecticide into mosquito netting. These results need to be further validated in a large-scale field trial to assess the durability and acceptability of this new tool for malaria vector control.
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影响因子：
11.8
作者：
Asidi A;N'Guessan R;Akogbeto M;Curtis C;Rowland M
通讯作者：
Rowland M
影响因子：
1.9
作者：
N'Guessan, R;Darriet, F;Carnevale, P
通讯作者：
Carnevale, P
影响因子：
1.7
作者：
Braks, Marieta A. H.;Carde, Ring T.
通讯作者：
Carde, Ring T.
DOI：
10.1073/pnas.0901369106
发表时间：
2009-07-14
影响因子：
11.1
作者：
Devine, Gregor J.;Zamora Perea, Elvira;Morrison, Amy C.
通讯作者：
Morrison, Amy C.
DOI：
10.1098/rstb.1998.0320
发表时间：
1998-10-29
期刊：
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
影响因子：
--
作者：
Hemingway, J;Hawkes, N;Ranson, H
通讯作者：
Ranson, H