Postoperative Delirium in Neurosurgical Patients: Recent Insights into the Pathogenesis.
Postoperative Delirium in Neurosurgical Patients: Recent Insights into the Pathogenesis.
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神经外科患者术后谵妄:发病机制的最新见解。
DOI:
10.3390/brainsci12101371
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发表时间:
2022-10-09
期刊:
影响因子:
3.3
通讯作者:
Lin, Guozhong
中科院分区:
文献类型:
--
作者:
Xu, Yinuo;Ma, Qianquan;Du, Haiming;Yang, Chenlong;Lin, Guozhong
Postoperative delirium (POD) is a complication characterized by disturbances in attention, awareness, and cognitive function that occur shortly after surgery or emergence from anesthesia. Since it occurs prevalently in neurosurgical patients and poses great threats to the well-being of patients, much emphasis is placed on POD in neurosurgical units. However, there are intricate theories about its pathogenesis and limited pharmacological interventions for POD. In this study, we review the recent insights into its pathogenesis, mainly based on studies within five years, and the five dominant pathological theories that account for the development of POD, with the intention of furthering our understanding and boosting its clinical management.
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