Impact of anxiety on quality of life in Parkinson's disease.
Impact of anxiety on quality of life in Parkinson's disease.
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DOI：
10.1155/2012/640707
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Cronin-Golomb A
中科院分区：
文献类型：
--
作者：
Hanna KK;Cronin-Golomb A
在帕金森氏症(PD)中，患者和医疗保健提供者都在寻找方法来保持患者的生活质量。许多研究集中于抑郁症和运动障碍对生活质量的影响，而忽视了焦虑的作用。我们使用帕金森氏病生活质量量表(PDQ-39)调查了焦虑和抑郁对帕金森病患者健康相关生活质量的影响。焦虑症状比抑郁、认知状态或运动阶段更显著地影响了38名轻至中度运动障碍的非痴呆患者的生活质量。逐步回归分析表明，焦虑可以解释PDQ-39总分的29%的变异，抑郁可以解释10%的变异，超出了焦虑的解释。研究结果表明，焦虑和抑郁的初级治疗对于优化PD患者的生活质量可能很重要。
In Parkinson's disease (PD), both the patient and the health care provider look for ways to preserve the patient's quality of life. Many studies focus on the impact of depression and motor disability on poor life quality but neglect to examine the role of anxiety. We investigated the impact of anxiety and depression on health-related quality of life in PD, using the Parkinson's Disease Quality of Life measure (PDQ-39). Symptoms of anxiety, more than depression, cognitive status, or motor stage, significantly affected quality of life in 38 nondemented patients with mild-to-moderate motor disability. Stepwise regression analyses revealed that anxiety explained 29% of the variance in the PDQ-39 sum score, and depression explained 10% of the variance beyond that accounted for by anxiety. The findings suggest that primary management of anxiety as well as depression may be important to optimizing the quality of life of PD patients.
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