Synaptic plasticity, neurogenesis, and functional recovery after spinal cord injury.
Synaptic plasticity, neurogenesis, and functional recovery after spinal cord injury.
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DOI：
10.1177/1073858408331372
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发表时间：
2009-04
期刊：
影响因子：
--
通讯作者：
Darian-Smith C
中科院分区：
文献类型：
--
作者：
Darian-Smith C
近年来，脊髓损伤的研究已经大大扩展，但我们对最初损伤后数周和数月内可能发生的功能恢复机制的理解还远远没有完成。为了掌握问题的范围，重要的是开始定义可能涉及脊髓损伤的感觉运动通路。这是在啮齿动物和非人灵长类动物中完成的，这是基础和转化性脊柱损伤研究中最常用的两种动物模型。许多更好地了解实验诱导模型，然后审查的途径，他们参与和重组和恢复，已被证明遵循。更好地理解神经元的机制介导的损伤后可塑性，包括树突棘的生长和轴突发芽，然后检查。
Spinal cord injury research has greatly expanded in recent years, but our understanding of the mechanisms that underlie the functional recovery that can occur over the weeks and months following the initial injury, is far from complete. To grasp the scope of the problem, it is important to begin by defining the sensorimotor pathways that might be involved by a spinal injury. This is done in the rodent and nonhuman primate, which are two of the most commonly used animal models in basic and translational spinal injury research. Many of the better known experimentally induced models are then reviewed in terms of the pathways they involve and the reorganization and recovery that have been shown to follow. The better understood neuronal mechanisms mediating such post-injury plasticity, including dendritic spine growth and axonal sprouting, are then examined.
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影响因子：
2.9
作者：
BASBAUM, AI;WALL, PD
通讯作者：
WALL, PD
软骨素酶ABC促进脊髓损伤后完整和受伤的脊柱系统的发芽。
DOI：
10.1523/jneurosci.2980-06.2006
发表时间：
2006-10-18
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Barritt AW;Davies M;Marchand F;Hartley R;Grist J;Yip P;McMahon SB;Bradbury EJ
通讯作者：
Bradbury EJ
DOI：
10.1073/pnas.262669099
发表时间：
2002-12-24
影响因子：
11.1
作者：
Corbetta, M;Burton, H;McDonald, JW
通讯作者：
McDonald, JW
影响因子：
3.4
作者：
Danilov, AI;Covacu, R;Brundin, L
通讯作者：
Brundin, L
影响因子：
2.9
作者：
CHANG, FLF;GREENOUGH, WT
通讯作者：
GREENOUGH, WT