A closed-loop electrical stimulation system triggered by EOG for acupuncture therapy
A closed-loop electrical stimulation system triggered by EOG for acupuncture therapy
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眼电触发闭环电刺激系统用于针灸治疗
DOI：
10.1080/21642583.2020.1733130
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发表时间：
2020-01
影响因子：
4.1
通讯作者：
Yuan Yang
中科院分区：
文献类型：
--
作者：
Ding Yuan;Yurong Li;Tian Wang;Jianguo Chen;Dongyi Chen;Dong Lin;Yuan Yang
针灸疗法是自闭症谱系障碍常用的中医干预方法。针灸通常由治疗师提供，因此，其有效性高度依赖于他们的经验。本文设计了一种神经生理信号触发的闭环电刺激治疗系统，以改进常规针灸在临床试验中的应用。当自闭症儿童观看专门设计的视觉唤醒系统时，眼电(EOG)信号被同步采集和分析。一旦注意力状态确定，电刺激就会被触发，将刺激传递到长强穴(尾骨和肛门之间)。三名健康志愿者和四名自闭症儿童参与了这项概念验证研究。在在线测试之前，离线确定了受试者专用的EOG模板。通过模板匹配算法得到健康儿童和自闭症儿童的平均识别率分别为95.45%和89.43%，平均误识别率分别为2.51%和7.23%。该系统能够识别注意状态的EOG模式，并成功触发电刺激。本研究首次将针灸与生物电信号相结合，为针灸治疗提供自动闭环电刺激系统。
Acupuncture therapy is an often-used traditional Chinese medicine intervention of autism spectrum disorder. Acupuncture is usually delivered by therapists; thus, its effectiveness highly relies on their experience. This paper designed a closed-loop electrical stimulation treatment system triggered by neurophysiological signals, in order to improve the conventional acupuncture in clinical trials. Electrooculogram (EOG) signals are collected and analyzed synchronously while autistic children are watching the specifically designed visual evocation system. The electrical stimulation is triggered once the attention state is determined, delivering stimulation to the Changqiang acupoint (between the tailbone and the anus). Three healthy volunteers and four autistic children participated in this proof-of-concept study. Prior to the online test, the subject-special EOG template was determined offline. We obtained the mean recognition rate of 95.45% for healthy participants and 89.43% for autistic children, and the mean false recognition rate of 2.51% for healthy participants and 7.23% for autistic children by template matching algorithm. The system was able to recognize the EOG pattern of attention to the state and successfully trigger the electrical stimulation. This study is the first time to combine acupuncture and bioelectrical signal to provide an automatic closed-loop electrical stimulation system for acupuncture therapy.
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