BacAnt: A Combination Annotation Server for Bacterial DNA Sequences to Identify Antibiotic Resistance Genes, Integrons, and Transposable Elements.
BacAnt: A Combination Annotation Server for Bacterial DNA Sequences to Identify Antibiotic Resistance Genes, Integrons, and Transposable Elements.
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BACANT:细菌DNA序列的组合注释服务器,以鉴定抗生素耐药性基因,整合元和转座元件。
DOI:
10.3389/fmicb.2021.649969
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发表时间:
2021
影响因子:
5.2
通讯作者:
Chen H
中科院分区:
文献类型:
--
作者:
Hua X;Liang Q;Deng M;He J;Wang M;Hong W;Wu J;Lu B;Leptihn S;Yu Y;Chen H
Whole genome sequencing (WGS) of bacteria has become a routine method in diagnostic laboratories. One of the clinically most useful advantages of WGS is the ability to predict antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs) in bacterial sequences. This allows comprehensive investigations of such genetic features but can also be used for epidemiological studies. A plethora of software programs have been developed for the detailed annotation of bacterial DNA sequences, such as rapid annotation using subsystem technology (RAST), Resfinder, ISfinder, INTEGRALL and The Transposon Registry. Unfortunately, to this day, a reliable annotation tool of the combination of ARGs and MGEs is not available, and the generation of genbank files requires much manual input. Here, we present a new webserver which allows the annotation of ARGs, integrons and transposable elements at the same time. The pipeline generates genbank files automatically, which are compatible with Easyfig for comparative genomic analysis. Our BacAnt code and standalone software package are available at https://github.com/xthua/bacant with an accompanying web application at http://bacant.net. Overall BacAnt’s service workflow. The figure is adapted with permissions from IntegronFinder.
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影响因子:
5.2
作者:
Leal, Nilma C.;Campos, Tulio L.;de-Melo-Neto, Osvaldo P.
通讯作者:
de-Melo-Neto, Osvaldo P.
影响因子:
5.2
作者:
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Song H
影响因子:
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Razavi, Mohammad;Kristiansson, Erik;Larsson, D. G. Joakim
通讯作者:
Larsson, D. G. Joakim
影响因子:
5.2
作者:
Zhou K;Lokate M;Deurenberg RH;Arends J;Lo-Ten Foe J;Grundmann H;Rossen JW;Friedrich AW
通讯作者:
Friedrich AW