Developmental respiratory physiology.
Developmental respiratory physiology.
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DOI：
10.1111/pan.14362
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发表时间：
2022-03
影响因子：
1.7
通讯作者：
von Ungern-Sternberg, Britta S.
中科院分区：
文献类型：
--
作者：
Trachsel, Daniel;Erb, Thomas O.;Hammer, Jurg;von Ungern-Sternberg, Britta S.
呼吸生理学的各个发育方面使婴幼儿呼吸衰竭的风险增加，这与麻醉期间更高的危重事件发生率有关。婴儿呼吸控制的不成熟反映在中枢性呼吸暂停和周期性呼吸延长，以及麻醉后呼吸暂停的风险增加。儿科上、下呼吸道的生理特点是具有较高的流动阻力和气道塌陷性。胸壁顺应性的增加和肺部气体交换面积的减少减少了肺氧储备，而代谢需氧量则较高，这会导致当换气受到影响时更快的氧气减饱和。这篇综述描述了呼吸生理学的各个发展方面，并总结了麻醉的含义。
Various developmental aspects of respiratory physiology put infants and young children at an increased risk of respiratory failure, which is associated with a higher rate of critical incidents during anesthesia. The immaturity of control of breathing in infants is reflected by prolonged central apneas and periodic breathing, and an increased risk of apneas after anesthesia. The physiology of the pediatric upper and lower airways is characterized by a higher flow resistance and airway collapsibility. The increased chest wall compliance and reduced gas exchange surface of the lungs reduce the pulmonary oxygen reserve vis‐à‐vis a higher metabolic oxygen demand, which causes more rapid oxygen desaturation when ventilation is compromised. This review describes the various developmental aspects of respiratory physiology and summarizes anesthetic implications.
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影响因子：
2.3
作者：
Cohen, G;Katz-Salamon, M
通讯作者：
Katz-Salamon, M
影响因子：
3.7
作者：
Bhalala US;Hemani M;Shah M;Kim B;Gu B;Cruz A;Arunachalam P;Tian E;Yu C;Punnoose J;Chen S;Petrillo C;Brown A;Munoz K;Kitchen G;Lam T;Bosemani T;Huisman TA;Allen RH;Acharya S
通讯作者：
Acharya S
影响因子：
5.7
作者：
Abrams, JT;Horrow, JC;Storella, RJ
通讯作者：
Storella, RJ
影响因子：
9.8
作者：
de la Grandville, Beatrice;Petak, Ferenc;Habre, Walid
通讯作者：
Habre, Walid
影响因子：
3.3
作者：
BROUILLETTE, RT;THACH, BT
通讯作者：
THACH, BT