Adult neurogenesis in the central olfactory pathway of dendrobranchiate and caridean shrimps: New insights into the evolution of the deutocerebral proliferative system in reptant decapods

Adult neurogenesis in the central olfactory pathway of dendrobranchiate and caridean shrimps: New insights into the evolution of the deutocerebral proliferative system in reptant decapods
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树鳃虾和虾虾中枢嗅觉通路的成体神经发生:对爬行动物十足目中大脑增殖系统进化的新见解

DOI:
10.1002/dneu.22596
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发表时间:
2018
影响因子:
3
通讯作者:
Harzsch S
Harzsch S
中科院分区:
医学3区
文献类型:
--
作者:
Wittfoth C;Harzsch S

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中枢嗅觉通路中持续的神经发生是许多爬行类十足动物,如龙虾、小龙虾和螃蟹的特征。在这些动物中,中脑增殖系统产生新的神经元,这些神经元整合到嗅觉系统的一级处理神经,即中脑化学感觉叶(也称为嗅叶)的神经元网络中。然而,小龙虾和小龙虾在表型和驱动成年神经发生的机制方面存在差异。虽然许多研究都集中在这些机制和成人神经发生的调节上,但关于系统发育分布的研究却缺失。为了从进化的角度研究十足类动物成年神经发生,我们利用胸腺嘧啶类似物溴脱氧尿苷(BrdU)作为循环细胞S期的标记物,研究了两个基本分化谱系的代表,即dendrobranchatepenaeus vannameia和carideanrangon crangona。与十足爬行动物相比,我们的研究结果表明,树突虾和齿状虾成年大脑中的神经发生机制更简单。所观察到的增殖速率和空间维度的差异被认为与嗅觉系统的复杂性有关。我们假设,随着另一种加工神经器官——副叶的出现,爬行动物的十足类动物进化出了一种更复杂、有丝分裂更活跃的增殖系统。©2018 Wiley期刊公司Develop Neurobiol, 2018
Persistent neurogenesis in the central olfactory pathway characterizes many reptant decapods such as lobsters, crayfish and crabs. In these animals, the deutocerebral proliferative system generates new neurons which integrate into the neuronal network of the first order processing neuropil of the olfactory system, the deutocerebral chemosensory lobes (also called olfactory lobes). However, differences concerning the phenotype and the mechanisms that drive adult neurogenesis were reported in crayfishversusspiny lobsters. While numerous studies have focussed on these mechanisms and regulation of adult neurogenesis, investigations about the phylogenetic distribution are missing. To contribute an evolutionary perspective on adult neurogenesis in decapods, we investigated two representatives of basally diverging lineages, the dendrobranchiatePenaeus vannameiand the carideanCrangon crangonusing the thymidine analogue Bromodeoxyuridine (BrdU) as marker for the S phase of cycling cells. Compared to reptant decapods, our results suggest a simpler mechanism of neurogenesis in the adult brain of dendrobranchiate and caridean shrimps. Observed differences in the rate of proliferation and spatial dimensions are suggested to correlate with the complexity of the olfactory system. We assume that a more complex and mitotically more active proliferative system in reptant decapods evolved with the emergence of another processing neuropil, the accessory lobes. © 2018 Wiley Periodicals, Inc. Develop Neurobiol, 2018
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