Revisiting the global workspace orchestrating the hierarchical organization of the human brain.
Revisiting the global workspace orchestrating the hierarchical organization of the human brain.
复制标题
重新审视全球工作空间,策划人脑的等级组织。
DOI:
10.1038/s41562-020-01003-6
复制
发表时间:
2021-04
影响因子:
29.9
通讯作者:
Kringelbach ML
中科院分区:
文献类型:
--
作者:
Deco G;Vidaurre D;Kringelbach ML
A central challenge in neuroscience is how the brain organizes the information necessary to orchestrate behaviour. Arguably, this whole-brain orchestration is carried out by a core subset of integrative brain regions, a ‘global workspace’, but its constitutive regions remain unclear. We quantified the global workspace as the common regions across seven tasks as well as rest, in a common ‘functional rich club’. To identify this functional rich club, we determined the information flow between brain regions by means of a normalized directed transfer entropy framework applied to multimodal neuroimaging data from 1,003 healthy participants and validated in participants with retest data. This revealed a set of regions orchestrating information from perceptual, long-term memory, evaluative and attentional systems. We confirmed the causal significance and robustness of our results by systematically lesioning a generative whole-brain model. Overall, this framework describes a complex choreography of the functional hierarchical organization of the human brain. Deco et al. use multimodal neuroimaging data to quantify the global workspace as the common ‘functional rich club’ of regions intersecting across seven tasks as well as rest.
登录
查看更多内容
影响因子:
6
作者:
Beer, A.;Biberacher, V.;Muehlau, M.
通讯作者:
Muehlau, M.
影响因子:
16.6
作者:
Atasoy S;Donnelly I;Pearson J
通讯作者:
Pearson J
DOI:
10.1111/j.2517-6161.1995.tb02031.x
发表时间:
1995-01-01
影响因子:
5.8
作者:
BENJAMINI, Y;HOCHBERG, Y
通讯作者:
HOCHBERG, Y
影响因子:
4.6
作者:
Atasoy S;Roseman L;Kaelen M;Kringelbach ML;Deco G;Carhart-Harris RL
通讯作者:
Carhart-Harris RL
影响因子:
5.3
作者:
Brovelli, Andrea;Chicharro, Daniel;Jirsa, Viktor
通讯作者:
Jirsa, Viktor