Comparison of the rate of refractive growth in aphakic eyes versus pseudophakic eyes in the Infant Aphakia Treatment Study.
Comparison of the rate of refractive growth in aphakic eyes versus pseudophakic eyes in the Infant Aphakia Treatment Study.
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DOI：
10.1016/j.jcrs.2016.09.021
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发表时间：
2016-12
影响因子：
2.8
通讯作者：
McClatchey, Scott K.
中科院分区：
文献类型：
--
作者：
Lambert, Scott R.;Cotsonis, George;DuBois, Lindreth;Wilson, M. Edward;Plager, David A.;Buckley, Edward G.;McClatchey, Scott K.
在婴儿无晶状体眼治疗研究（IATS）中比较无晶状体眼和人工晶状体眼之间的屈光增长速率。
美国的12个临床站点。
随机临床试验。
在IATS中被随机分配接受单侧白内障摘除联合角膜接触镜矫正与人工晶状体（IOL）植入的患者，其屈光增长速率（RRG3）是根据从术后1个月检查到5岁时的屈光变化计算得出的。RRG3是一个对数公式，用于计算儿童的屈光增长速率。采用两组t检验比较角膜接触镜组和IOL组之间的平均屈光增长以及基于手术年龄和视力的结果。
对IATS中招募的114例患者中的108例的纵向屈光数据进行了研究（角膜接触镜组，n = 54；IOL组，n = 54）。角膜接触镜组（-18.0屈光度[D]±11.0[标准差]）和IOL组（-19.0±9.0 D）的平均RRG3相似（P = 0.49）。IOL组中RRG3值与白内障手术年龄、青光眼状况或视力结果无关。在无晶状体眼组中，只有视力结果与屈光增长相关（P = 0.01）。
婴儿单侧白内障手术后，无论是否植入IOL，眼睛的屈光增长速率相似。无晶状体眼（而非人工晶状体眼）视力较差与较高的屈光增长速率相关。
To compare the rate of refractive growth between aphakic eyes and pseudophakic eyes in the Infant Aphakia Treatment Study (IATS). Twelve clinical sites across the United States. Randomized clinical trial. Patients randomized to unilateral cataract extraction with contact lens correction versus intraocular lens (IOL) implantation in the IATS had their rate of refractive growth (RRG3) calculated based on the change in refraction from the 1-month postoperative examination to age 5 years. The RRG3 is a logarithmic formula designed to calculate the rate of refractive growth in children. Two-group t tests were used to compare the mean refractive growth between the contact lens group and IOL group and outcomes based on age at surgery and visual acuity. Longitudinal refractive data were studied for 108 of 114 patients enrolled in the IATS (contact lens group, n = 54; IOL group, n = 54). The mean RRG3 was similar in the contact lens group (−18.0 diopter [D] ± 11.0 [SD]) and the IOL group (−19.0 ± 9.0 D) (P = .49). The RRG3 value was not correlated with age at cataract surgery, glaucoma status, or visual outcome in the IOL group. In the aphakia group, only visual outcome was correlated with refractive growth (P = .01). Infants’ eyes had a similar rate of refractive growth after unilateral cataract surgery whether or not an IOL was implanted. A worse visual outcome was associated with a higher rate of refractive growth in aphakic, but not pseudophakic, eyes.
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影响因子：
1.6
作者：
Crouch, ER;Crouch, ER;Pressman, SH
通讯作者：
Pressman, SH
影响因子：
8.1
作者：
Freedman SF;Lynn MJ;Beck AD;Bothun ED;Örge FH;Lambert SR;Infant Aphakia Treatment Study Group
通讯作者：
Infant Aphakia Treatment Study Group
影响因子：
--
作者：
Lambert, Scott R.;Buckley, Edward G.;Ward, Michael
通讯作者：
Ward, Michael
影响因子：
13.7
作者：
Lambert, Scott R.;Melia, Michele;Yang, Michael B.
通讯作者：
Yang, Michael B.
影响因子：
--
作者：
Beck, Allen D.;Freedman, Sharon F.;Lynn, Michael J.;Bothun, Erick;Neely, Daniel E.;Lambert, Scott R.
通讯作者：
Lambert, Scott R.