Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)
Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)
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亲水和疏水链段接枝聚氯乙烯的比较研究
DOI：
10.1007/s10118-018-2034-x
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发表时间：
2018-01
影响因子：
4.3
通讯作者：
Zhang Tao
中科院分区：
文献类型：
--
作者：
Zhang Yan;Yuan Zipeng;Qin Yu;Dai Ji;Zhang Tao
聚氯乙烯（PVC）是世界上产量最大的塑料之一，广泛用于一次性医疗器械。然而，PVC所必需的添加剂常常引起人们对其安全性的担忧，从而对PVC本身的改性提出了要求。本研究将聚乙二醇（PEG）和聚二甲基硅氧烷（PDMS）以相似的方式接枝到聚氯乙烯骨架上，并利用傅里叶变换红外光谱、x射线光电子能谱、热重分析和差示扫描量热法对改性聚氯乙烯的化学结构进行了表征。并对不同材料表面的水接触角、蛋白质吸附、血小板粘附、细胞附着和增殖进行了研究和比较。结果表明，PEG和PDMS接枝均比裸PVC具有更好的生物相容性，而疏水性PDMS接枝的PVC比亲水性PEG接枝的PVC更能促进细胞的附着和增殖。
Poly(vinyl chloride) (PVC) is one of the mostly produced plastics in the world and is widely used in single-use medical devices. However, the additives that are often necessary for PVC arouse concerns of its safety, thus quests the modifications of PVC itself. In this study, poly(ethylene glycol) (PEG) and polydimethylsiloxane (PDMS) segments were grafted onto PVC backbone in similar ways, and the chemical structures of the modified PVCs were characterized by Fourier transform infrared spectra, X-ray photoelectron spectra, thermogravimetric analysis and differential scanning calorimetry. Moreover, the water contact angle, protein adsorption, platelet adhesion, cell attachment and proliferation on different material surfaces were studied and compared. It was found that both PEG and PDMS grafting yielded improvement on biocompatibility compared with bare PVC, while hydrophobic PDMS grafted PVC showed more effective on cell attachment and proliferation than that of hydrophilic PEG grafted PVC.
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影响因子：
14
作者：
Kainthan, Rajesh Kumar;Gnanamani, Muthiah;Kizhakkedathu, Jayachandran N.
通讯作者：
Kizhakkedathu, Jayachandran N.
DOI：
10.1002/14356007.a21_717
发表时间：
2000-06
期刊：
--
影响因子：
--
作者：
M. Allsopp;G. Vianello
通讯作者：
M. Allsopp;G. Vianello
影响因子：
14
作者：
S. Lakshmi;A. Jayakrishnan
通讯作者：
S. Lakshmi;A. Jayakrishnan
影响因子：
4.6
作者：
A. Neffe;M. von Ruesten-Lange;S. Braune;K. Luetzow;T. Roch;K. Richau;F. Jung;A. Lendlein
通讯作者：
A. Neffe;M. von Ruesten-Lange;S. Braune;K. Luetzow;T. Roch;K. Richau;F. Jung;A. Lendlein
影响因子：
2.4
作者：
Lakshmi, S;Jayakrishnan, A
通讯作者：
Jayakrishnan, A