Introducing rapid oral-fluid HIV testing among high risk populations in Shandong, China: feasibility and challenges.
Introducing rapid oral-fluid HIV testing among high risk populations in Shandong, China: feasibility and challenges.
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DOI：
10.1186/1471-2458-14-422
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发表时间：
2014-05-03
影响因子：
4.5
通讯作者：
Ma W
中科院分区：
文献类型：
--
作者：
Marley G;Kang D;Wilson EC;Huang T;Qian Y;Li X;Tao X;Wang G;Xun H;Ma W
本研究旨在确定在中国使用快速口腔液检测作为替代HIV检测方法的可行性。本研究采用混合方法对山东省4个城市的男男性行为者（MSM）、女性性工作者（FSW）和VCT客户进行了研究。通过面对面访谈，对1137名参与者进行了预测试问卷，以评估人口统计学特征、艾滋病毒检测史和接受快速口服液检测的意愿。为VCT患者提供唾液检测试剂盒进行筛查，并记录操作错误。将口腔和血液检测结果进行比较。对200名接受过口头测试的外籍工作人员进行了简短的反馈问卷调查。MSM、FSW和VCT患者接受口腔液体HIV检测的意愿率分别为72.8%、72.1%和67.4%。229名VCT客户在测试试剂盒操作过程中记录的常见错误包括：准备不足、拭子取样错误、稀释错误、测试错误以及无法读取测试结果。参与者列举的口腔测试的优点包括：干扰小、无痛、自我测试容易和隐私。缺点包括认为结果不可靠（55.5%）和未得到国家认可（9%）。唾液检测结果与血液检测结果的符合率为0.970 (χ2 = 153.348, P < 0.001)，一致性较好。在中国引入口服快速液体检测作为一种替代HIV检测方法是非常可行的，但也存在一些挑战，包括低识别率和操作错误。
This study was conducted to ascertain the feasibility of using rapid oral fluid testing as an alternative HIV testing method in China. This is a mixed-method study among men who have sex with men (MSM), female sex workers (FSW) and VCT clients, conducted in 4 cities in Shandong Province. A pre-tested questionnaire was administered to 1137 participants through face-to-face interview to assess demographic characteristics, HIV testing histories and willingness to accept rapid oral fluid testing. VCT clients were provided with the saliva test kits for a screening test and errors in operation were recorded. Testing results were compared between oral and blood testing. Short feedback questionnaire was administered to 200 FSW who had undergone oral testing. The rate of willingness to take oral-fluid HIV testing among MSM, FSW and VCT clients was 72.8%, 72.1% and 67.4% respectively. Common errors recorded during test kit operation by the 229 VCT clients included: unpreparedness, wrong swab sampling, wrong dilution, wrong testing and inability to read test results. Advantages of oral testing listed by participants included: less intrusive, painlessness, easy self- testing and privacy. Disadvantages included perceived unreliable results (55.5%) and not nationally recognised (9%). Comparison of saliva and the blood testing results recorded a consistency rate of 0.970 (χ2 = 153.348, P < 0.001), implying an excellent consistency. Introduction of oral rapid fluid testing as an alternative HIV testing method in China is highly feasible but with some challenges including low recognition and operation errors.
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影响因子：
3.7
作者：
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DOI：
10.1097/00126334-200303010-00012
发表时间：
2003-03-01
影响因子：
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作者：
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通讯作者：
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