Effects of Endurance-Focused Physical Activity Interventions on Brain Health: A Systematic Review.

Effects of Endurance-Focused Physical Activity Interventions on Brain Health: A Systematic Review.
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DOI:
10.1177/1099800416660758
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发表时间:
2017-01
影响因子:
2.5
通讯作者:
Arfanakis K
Arfanakis K
中科院分区:
医学4区
文献类型:
--
作者:
Halloway S;Wilbur J;Schoeny ME;Arfanakis K

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专注于改善老年人认知功能的身体活动干预研究除了神经认知测量之外,越来越多地使用磁共振成像 (MRI) 测量来评估对大脑的影响。本系统评价的目的是确定以耐力为重点的体力活动随机临床试验 (RCT) 干预措施对大脑的影响,通过 MRI 测量,对社区居住的无认知障碍的中年或老年人进行测量。检索了五个电子数据库。最终样本包括六项研究。没有一项研究报告了参与者的种族或民族特征。除了 MRI 之外,所有研究还包括神经认知测量。六项干预措施中的五项包括基于实验室的跑步机或自行车监督锻炼课程,而一项包括基于社区的体育活动。在一项研究中,身体活动测量仅限于心肺健康和计步器的评估。由于缺乏足够的数据报告,仅计算了一项 MRI 测量研究和两项神经认知测量研究的效应大小。 MRI 测量的效应大小范围为 d = 0.2-0.3,神经认知测量的效应大小范围为 0.2-32。个别研究的结果表明,MRI 测量可能比神经认知测量对身体活动的影响更敏感。未来的研究需要包括多样化的、基于社区的参与者、身体活动的直接测量以及 MRI 和神经认知发现的完整报告。
Physical activity intervention studies that focus on improving cognitive function in older adults have increasingly used magnetic imaging resonance (MRI) measures in addition to neurocognitive measures to assess effects on the brain. The purpose of this systematic review was to identify the effects of endurance-focused physical activity randomized clinical trial (RCT) interventions on the brain as measured by MRI in community-dwelling middle-aged or older adults without cognitive impairment. Five electronic databases were searched. The final sample included six studies. None of the studies reported racial or ethnic characteristics of the participants. All studies included neurocognitive measures in addition to MRI. Five of the six interventions included laboratory-based treadmill or bike supervised exercise sessions, while one included community-based physical activity. Physical activity measures were limited to assessment of cardiorespiratory fitness, and pedometer in one study. Due to the lack of adequate data reported, effect sizes were calculated for only one study for MRI measures and two studies for neurocognitive measures. Effect sizes ranged from d = .2-.3 for MRI measures and .2–32 for neurocognitive measures. Findings of the individual studies suggest that MRI measures may be more sensitive to the effects of physical activity than neurocognitive measures. Future studies are needed that include diverse, community-based participants, direct measures of physical activity, and complete reporting of MRI and neurocognitive findings.
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