Changing Knowledge and Attitudes Towards HIV Treatment-as-Prevention and "Undetectable = Untransmittable": A Systematic Review.
Changing Knowledge and Attitudes Towards HIV Treatment-as-Prevention and "Undetectable = Untransmittable": A Systematic Review.
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DOI：
10.1007/s10461-021-03296-8
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发表时间：
2021-12
影响因子：
4.4
通讯作者：
Onoya D
中科院分区：
文献类型：
--
作者：
Bor J;Fischer C;Modi M;Richman B;Kinker C;King R;Calabrese SK;Mokhele I;Sineke T;Zuma T;Rosen S;Bärnighausen T;Mayer KH;Onoya D
接受艾滋病毒治疗的人不能通过性传播艾滋病毒（不可检测=不可传播，U = U）。然而，治疗即预防（TasP）的科学可能不会被艾滋病毒感染者和非艾滋病毒感染者广泛理解，他们可以从这些信息中受益。我们系统地回顾了与TasP相关的知识和态度以及提供TasP或U = U信息的干预措施的全球文献。我们纳入了2008-2020年发表的对世界各地的供应商、患者和社区的研究。我们筛选了885篇论文和摘要，确定了72篇纳入。在高收入环境中进行的研究报告说，人们对TasP的认识很高，但对无法检测到的艾滋病毒传播可能性的认识存在差距。更多的知识与更积极的态度TasP。现有的文献显示，非洲对TasP的认识很低，那里有三分之二的艾滋病毒感染者。新出现的证据表明，干预措施提供信息的TasP知识，耻辱，艾滋病毒检测和病毒抑制的有益影响。审查已在PROSPERO预注册：CRD 42020153725在线版本包含补充材料，可通过10.1007/s10461-021-03296-8获得。
People on HIV treatment with undetectable virus cannot transmit HIV sexually (Undetectable = Untransmittable, U = U). However, the science of treatment-as-prevention (TasP) may not be widely understood by people with and without HIV who could benefit from this information. We systematically reviewed the global literature on knowledge and attitudes related to TasP and interventions providing TasP or U = U information. We included studies of providers, patients, and communities from all regions of the world, published 2008–2020. We screened 885 papers and abstracts and identified 72 for inclusion. Studies in high-income settings reported high awareness of TasP but gaps in knowledge about the likelihood of transmission with undetectable HIV. Greater knowledge was associated with more positive attitudes towards TasP. Extant literature shows low awareness of TasP in Africa where 2 in 3 people with HIV live. The emerging evidence on interventions delivering information on TasP suggests beneficial impacts on knowledge, stigma, HIV testing, and viral suppression. Review was pre-registered at PROSPERO: CRD42020153725 The online version contains supplementary material available at 10.1007/s10461-021-03296-8.
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作者：
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发表时间：
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影响因子：
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