Factor Structure of the Bern Psychopathology Scale in a Sample of Patients with Schizophrenia Spectrum Disorders

Factor Structure of the Bern Psychopathology Scale in a Sample of Patients with Schizophrenia Spectrum Disorders
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精神分裂症谱系障碍患者样本中伯尔尼精神病理学量表的因子结构

DOI:
10.1016/j.eurpsy.2015.07.010
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发表时间:
2015
影响因子:
7.8
通讯作者:
Jäger M
Jäger M
中科院分区:
医学2区
文献类型:
--
作者:
Lang FU;Stierlin AS;Stegmayer K;Walther S;Becker T;Jäger M

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背景伯尔尼精神病理学量表(BPS)是基于一种系统特有的方法对精神分裂症的精神病理症状模式进行分类的。它由三个领域(语言、情感和运动行为)的子量表组成,假设这三个领域与特定的大脑回路有关。本研究的目的是考察精神分裂症谱系障碍患者的BPS的因素结构。方法选择德国乌尔姆大学精神病学II教研室(n=100)和瑞士伯尔尼大学精神病学医院(n=49)的149例精神分裂症谱系障碍住院患者。采用BPS评定患者的精神病理状态。结果共识别出6类(抑制语言、抑制运动行为、抑制情感、非抑制情感、非抑制语言/运动行为、抑制语言/运动行为、抑制语言/运动行为),可解释40.13%的数据变异。尽管在语言和运动行为领域之间发现了重叠,但将属性划分为抑制和非抑制类是合适的。结论BPS量表在识别精神分裂症谱系障碍亚型方面具有较好的效度。未来的研究应该解决维度精神病理症状的纵向评估,并阐明潜在的神经生物学过程。
BackgroundThe Bern Psychopathology Scale (BPS) is based on a system-specific approach to classifying the psychopathological symptom pattern of schizophrenia. It consists of subscales for three domains (language, affect and motor behaviour) that are hypothesized to be related to specific brain circuits. The aim of the study was to examine the factor structure of the BPS in patients with schizophrenia spectrum disorders.MethodsOne hundred and forty-nine inpatients with schizophrenia spectrum disorders were recruited at the Department of Psychiatry II, Ulm University, Germany (n = 100) and at the University Hospital of Psychiatry, Bern, Switzerland (n = 49). Psychopathology was assessed with the BPS. The VARCLUS procedure of SAS® (a type of oblique component analysis) was used for statistical analysis.ResultsSix clusters were identified (inhibited language, inhibited motor behaviour, inhibited affect, disinhibited affect, disinhibited language/motor behaviour, inhibited language/motor behaviour) which explained 40.13% of the total variance of the data. A binary division of attributes into an inhibited and disinhibited cluster was appropriate, although an overlap was found between the language and motor behaviour domains. There was a clear distinction between qualitative and quantitative symptoms.ConclusionsThe results argue for the validity of the BPS in identifying subsyndromes of schizophrenia spectrum disorders according to a dimensional approach. Future research should address the longitudinal assessment of dimensional psychopathological symptoms and elucidate the underlying neurobiological processes.
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发表时间: 2015-08
影响因子: 7.3
作者:
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发表时间: 2013-11
影响因子: 6.6
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