E-cigarette use among smokers with serious mental illness.

E-cigarette use among smokers with serious mental illness.
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DOI:
10.1371/journal.pone.0113013
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Grana RA
Grana RA
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Prochaska JJ;Grana RA

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在一项临床试验中,我们研究了电子烟(EC)的使用、使用的相关性以及严重精神疾病吸烟者吸烟行为的相关变化。成人吸烟者是在2009年至2013年期间在旧金山湾区的急性精神病住院期间招募的(N = 956,在接近吸烟者中有73%的人参加了该计划)。在基线时,参与者在19年(SD = 14)中平均每天吸烟17支(SD = 10);24%的人打算在下个月戒烟。分析检查了18个月试验中报告的EC使用频率和相关性,以及EC使用状态对吸烟行为的影响。EC的总体使用率为11%,按注册年份计算,从2009年的0%增加到2013年的25%。在多元Logistic回归中,对于18-26岁的人,以及处于变化的准备阶段和预想阶段的人,使用EC的可能性随着招募的每一年的增加而显著增加,而在西班牙裔参与者中不太可能。在基线水平,EC的使用与性别、精神诊断和烟草依赖的测量无关。此外,在为期18个月的试验中,EC的使用与吸烟状况的变化或在持续吸烟者中每天减少香烟的数量无关。在对患有严重精神疾病的吸烟者进行的临床试验中,EC的使用量随着时间的推移而增加,特别是在年轻人和打算戒烟的人中。EC的使用与吸烟的变化无关。这些发现具有临床意义,值得进一步研究。
We examined electronic cigarette (EC) use, correlates of use, and associated changes in smoking behavior among smokers with serious mental illness in a clinical trial. Adult smokers were recruited during acute psychiatric hospitalization (N = 956, 73% enrollment among approached smokers) in the San Francisco Bay Area between 2009–2013. At baseline, participants averaged 17 (SD = 10) cigarettes per day for 19 (SD = 14) years; 24% intended to quit smoking in the next month. Analyses examined frequency and correlates of EC use reported over the 18-month trial and changes in smoking behavior by EC use status. EC use was 11% overall, and by year of enrollment, increased from 0% in 2009 to 25% in 2013. In multiple logistic regression, the likelihood of EC use was significantly greater with each additional year of recruitment, for those aged 18–26, and for those in the preparation versus precontemplation stage of change, and unlikely among Hispanic participants. EC use was unrelated to gender, psychiatric diagnosis, and measures of tobacco dependence at baseline. Further, over the 18-month trial, EC use was not associated with changes in smoking status or, among continued smokers, with reductions in cigarettes per day. Within a clinical trial with smokers with serious mental illness, EC use increased over time, particularly among younger adults and those intending to quit tobacco. EC use was unrelated to changes in smoking. The findings are of clinical interest and warrant further study.
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