Cerebellar control of thalamocortical circuits for cognitive function: A review of pathways and a proposed mechanism.
Cerebellar control of thalamocortical circuits for cognitive function: A review of pathways and a proposed mechanism.
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DOI：
10.3389/fnsys.2023.1126508
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发表时间：
2023
影响因子：
3
通讯作者：
Liu, Yu
中科院分区：
文献类型：
--
作者：
Heck, Detlef H.;Fox, Mia B.;Chapman, Brittany Correia;McAfee, Samuel S.;Liu, Yu
关键词：
There is general agreement that cerebrocerebellar interactions via cerebellothalamocortical pathways are essential for a cerebellar cognitive and motor functions. Cerebellothalamic projections were long believed target mainly the ventral lateral (VL) and part of the ventral anterior (VA) nuclei, which project to cortical motor and premotor areas. Here we review new insights from detailed tracing studies, which show that projections from the cerebellum to the thalamus are widespread and reach almost every thalamic subnucleus, including nuclei involved in cognitive functions. These new insights into cerebellothalamic pathways beyond the motor thalamus are consistent with the increasing evidence of cerebellar cognitive function. However, the function of cerebellothalamic pathways and how they are involved in the various motor and cognitive functions of the cerebellum is still unknown.我们简要回顾了有关丘脑在协调新皮质神经元振荡一致性中的作用的文献。 The coherence of oscillations, which measures the stability of the phase relationship between two oscillations of the same frequency, is considered an indicator of increased functional connectivity between two structures showing coherent oscillations. Through thalamocortical interactions coherence patterns dynamically create and dissolve functional cerebral cortical networks in a task dependent manner.最后，我们回顾了小脑参与协调大脑皮层结构之间振荡的一致性的证据。 We conclude that cerebellothalamic pathways provide the necessary anatomical substrate for a proposed role of the cerebellum in coordinating neuronal communication between cerebral cortical areas by coordinating the coherence of oscillations.
There is general agreement that cerebrocerebellar interactions via cerebellothalamocortical pathways are essential for a cerebellar cognitive and motor functions. Cerebellothalamic projections were long believed target mainly the ventral lateral (VL) and part of the ventral anterior (VA) nuclei, which project to cortical motor and premotor areas. Here we review new insights from detailed tracing studies, which show that projections from the cerebellum to the thalamus are widespread and reach almost every thalamic subnucleus, including nuclei involved in cognitive functions. These new insights into cerebellothalamic pathways beyond the motor thalamus are consistent with the increasing evidence of cerebellar cognitive function. However, the function of cerebellothalamic pathways and how they are involved in the various motor and cognitive functions of the cerebellum is still unknown. We briefly review literature on the role of the thalamus in coordinating the coherence of neuronal oscillations in the neocortex. The coherence of oscillations, which measures the stability of the phase relationship between two oscillations of the same frequency, is considered an indicator of increased functional connectivity between two structures showing coherent oscillations. Through thalamocortical interactions coherence patterns dynamically create and dissolve functional cerebral cortical networks in a task dependent manner. Finally, we review evidence for an involvement of the cerebellum in coordinating coherence of oscillations between cerebral cortical structures. We conclude that cerebellothalamic pathways provide the necessary anatomical substrate for a proposed role of the cerebellum in coordinating neuronal communication between cerebral cortical areas by coordinating the coherence of oscillations.
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影响因子：
16.2
作者：
Bosman CA;Schoffelen JM;Brunet N;Oostenveld R;Bastos AM;Womelsdorf T;Rubehn B;Stieglitz T;De Weerd P;Fries P
通讯作者：
Fries P
影响因子：
5.3
作者：
Angulo-Garcia, David;Ferraris, Maeva;Quilichini, Pascale P.
通讯作者：
Quilichini, Pascale P.
影响因子：
2.5
作者：
AERTSEN, AMHJ;GERSTEIN, GL;PALM, G
通讯作者：
PALM, G
内侧丘脑和腹内侧丘脑参与前额皮质中不同的 L1 回路。
影响因子：
16.2
作者：
Anastasiades PG;Collins DP;Carter AG
通讯作者：
Carter AG
影响因子：
5.8
作者：
Bjerke IE;Yates SC;Laja A;Witter MP;Puchades MA;Bjaalie JG;Leergaard TB
通讯作者：
Leergaard TB