The Predictive Value of Leukocyte Parameters for Hypertensive Disorders of Pregnancy in South China
The Predictive Value of Leukocyte Parameters for Hypertensive Disorders of Pregnancy in South China
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白细胞参数对华南地区妊娠期高血压疾病的预测价值
DOI：
10.3109/10641955.2010.507836
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发表时间：
2012-02
影响因子：
1.5
通讯作者：
Wang, Jieling
中科院分区：
文献类型：
--
作者：
Yang, Hongling;Wang, Qian;Tang, Wen;Zhu, Chunyan;Xiao, Yanqing;Wang, Jieling
客观的。评估白细胞参数对妊娠期高血压疾病（HDP）的预测价值。方法。本研究共纳入 523 例 HDP 患者和 853 例正常妊娠。比较各组妊娠不同阶段的白细胞参数，并计算临床诊断效率，分析这些参数对HDP的预测价值。结果。与正常妊娠妇女相比，患有 HDP 的女性在妊娠中期的白细胞参数显着升高，而在妊娠末期的白细胞参数显着降低。在 HDP 临床综合征出现之前，观察到几个参数明显增加；中性粒细胞 (NEU) 和嗜碱性粒细胞 (Baso) 增加预测 HDP 的优势比分别为 1.02 和 1.16 (p < 0.01)。 NEU高于6.12 × 109/L时预测HDP 13~20周的敏感度为71.95%，Baso高于0.053 × 109/L时特异度为71.01%。结论。 NEU 和 Baso 有助于预测症状前期的 HDP。
Objective. To evaluate the predictive values of the leukocyte parameters for hypertensive disorders in pregnancy (HDP). Methods. A total of 523 HDP patients and 853 normal pregnancies were included in the present study. The leukocyte parameters in different stages of pregnancy were compared among the groups, and the efficiency of clinical diagnosis was calculated to analyze the predictive value of these parameters to HDP. Results. Women with HDP presented significantly higher leukocyte parameters in the second trimester and significantly lower values in the last trimester as compared to the normal gravidas. An evident increase of several parameters was observed preceding the clinical syndromes of HDP; and the odds ratio of increased neutrophil (NEU) and basophil (Baso) for predicting HDP were 1.02 and 1.16 (p < 0.01), respectively. The sensitivity of NEU was 71.95% when it was higher than 6.12 × 109/L, and the specificity of Baso was 71.01% when it was higher than 0.053 × 109/L for the prediction of HDP in 13–20 weeks. Conclusion. The NEU and Baso are helpful for predicting HDP during the presymptom period.
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DOI：
10.1016/s0140-6736(05)17987-2
发表时间：
2005-03
期刊：
The Lancet
影响因子：
--
作者：
B. Sibai;G. Dekker;M. Kupferminc
通讯作者：
B. Sibai;G. Dekker;M. Kupferminc
DOI：
10.1007/978-3-030-16481-2_34
发表时间：
2019
期刊：
Textbook of Vascular Medicine
影响因子：
--
作者：
D. Carty
通讯作者：
D. Carty
影响因子：
81.5
作者：
Dimitriadis, Evdokia;Rolnik, Daniel L.;Menkhorst, Ellen
通讯作者：
Menkhorst, Ellen
影响因子：
2.8
作者：
Haukkamaa, L;Salminen, M;Kaaja, R
通讯作者：
Kaaja, R
影响因子：
2.1
作者：
Lurie, S;Frenkel, E;Tuvbin, Y
通讯作者：
Tuvbin, Y