The ecology and adaptive evolution of influenza A interspecies transmission.

The ecology and adaptive evolution of influenza A interspecies transmission.
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流感的生态和适应性演变种间传播。

DOI:
10.1111/irv.12412
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发表时间:
2017-01
影响因子:
4.4
通讯作者:
Smith GJ
Smith GJ
中科院分区:
医学4区
文献类型:
--
作者:
Joseph U;Su YC;Vijaykrishna D;Smith GJ

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自2013年以来,发生了几起令人震惊的流感相关事件;高致病性H5禽流感病毒在北美的传播,H10N8和H5N6人畜共患病感染的发现,中国正在发生的H7N9感染以及亚洲和中东部分地区持续发生的H5N1病毒人畜共患病。新的流感大流行的风险随着物种间传播事件的重复增加而增加,这促进了动物流感毒株之间的重新组合;因此,了解促进或阻碍甲型流感病毒跨物种传播的相关因素至关重要。在这里,我们概述了iav的生态学和进化适应性,重点介绍了使各种病毒基因片段能够在种间传播的分子因素。
Since 2013, there have been several alarming influenza‐related events; the spread of highly pathogenic avian influenza H5 viruses into North America, the detection of H10N8 and H5N6 zoonotic infections, the ongoing H7N9 infections in China and the continued zoonosis of H5N1 viruses in parts of Asia and the Middle East. The risk of a new influenza pandemic increases with the repeated interspecies transmission events that facilitate reassortment between animal influenza strains; thus, it is of utmost importance to understand the factors involved that promote or become a barrier to cross‐species transmission of Influenza A viruses (IAVs). Here, we provide an overview of the ecology and evolutionary adaptations of IAVs, with a focus on a review of the molecular factors that enable interspecies transmission of the various virus gene segments.
DOI: 10.1086/524991
发表时间: 2008-02-15
影响因子: 6.4
作者:
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通讯作者: Edwards, Scott V.
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