Canalization of arousal in the preweanling rat: effects of amphetamine on aggregation with surrogate stimuli.

Canalization of arousal in the preweanling rat: effects of amphetamine on aggregation with surrogate stimuli.
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断奶前大鼠觉醒的管道化:安非他明对替代刺激聚集的影响。

DOI:
10.1002/dev.420140206
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发表时间:
1981
影响因子:
2.2
通讯作者:
Raskin,LA
Raskin,LA
中科院分区:
心理学4区
文献类型:
--
作者:
Campbell,BA;Raskin,LA

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将15日龄的断奶前大鼠置于一个不熟悉的笼中,笼中含有多种替代同种刺激物中的一种。替代刺激物由覆盖有柔软蓬松的合成毛皮的大鼠大小的铝管、晒黑的大鼠毛皮、毛毡和铝板组成。将替代物保持在环境温度或加热至体表温度(37°C)。第一个实验表明,替代刺激的毛皮(毛皮的长度和柔软度)和温度是同种聚集(蜷缩)的重要决定因素。第二个实验表明,对柔软蓬松的替代品的偏好并不受温度守恒的影响,因为当环境温度升高到热中性(33°C)时,可以获得相同的蜷缩行为。最后的实验表明,安非他明限制了范围内的替代刺激,引起蜷缩在断奶前的大鼠。安非他明产生一个陡峭的泛化梯度的方法替代刺激的发现进一步证实了我们以前的假设,安非他明渠道唤醒对突出的环境刺激。这些发现对使用安非他明治疗多动症儿童具有启示作用。
Preweanling rats, 15 days of age, were placed in an unfamiliar cage containing 1 of a variety of surrogate conspecific stimuli. The surrogate stimuli consisted of a rat‐sized aluminum tube covered with soft fluffy synthetic fur, a tanned rat pelt, felt, and an aluminum sheet. The surrogate was either maintained at ambient temperature of heated to body surface temperature (37°C). The 1st experiment revealed that both furriness (length and softness of fur) and temperature of the surrogate stimulus are important determinants of conspecific aggregation (huddling). The 2nd experiment demonstrated that preference for the soft, fluffy surrogate was not mediated by temperature conservation by showing that the same huddling behavior was obtained when ambient temperature was raised to thermoneutrality (33°C). The final experiment demonstrated that amphetamine restricted the range of surrogate stimuli that elicited huddling in the preweanling rat. The finding that amphetamine produces a steeper generalization gradient of approach to surrogate stimuli further confirms our previous hypothesis that amphetamine canalizes arousal toward salient environmental stimuli. These findings have implications for the use of amphetamines to treat hyperkinetic children.
DOI: 10.1038/scientificamerican0659-68
发表时间: 1959-01-01
影响因子: 3
作者:
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发表时间: 1976-01-01
期刊: SCIENCE
影响因子: 56.9
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DOI: --
发表时间: 1969
期刊: Science
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发表时间: 1973
影响因子: 5.2
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通讯作者: F. M. Hewett