Impact of imaging approach on radiation dose and associated cancer risk in children undergoing cardiac catheterization.
Impact of imaging approach on radiation dose and associated cancer risk in children undergoing cardiac catheterization.
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DOI：
10.1002/ccd.26630
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发表时间：
2017-04
影响因子：
2.3
通讯作者：
Yoshizumi, Terry K.
中科院分区：
文献类型：
--
作者：
Hill, Kevin D.;Wang, Chu;Einstein, Andrew J.;Januzis, Natalie;Giao Nguyen;Li, Jennifer S.;Fleming, Gregory A.;Yoshizumi, Terry K.
量化图像优化对接受心导管手术的儿童吸收辐射剂量和相关风险的影响。各种成像和透视系统的技术参数，包括相机放大率、源像距离、准直、抗散射网格、光束质量和脉冲速率，都影响辐射剂量，但尚未在幼儿中得到很好的研究。我们使用拟人模型（年龄：新生儿和5岁）来测量各种成像方法的表面辐射暴露，并使用蒙特卡罗模拟估计吸收器官剂量和有效剂量（ED）。在美国国家科学院电离辐射生物学效应VII报告中开发的模型用于比较针对剂量减少优化的成像方案与次优成像方案（+20cm源到像距离，+1放大设置，无准直）对癌症终生归因风险（LAR）的影响。对于新生儿和5岁的幻影，ED的变化如下：从6英寸放大到10英寸放大时，ED的变化分别为+157%和+232%；+61%和+59%的源到像距离增加20cm；−42%和−48%，外加1英寸外围准直；- 31%和- 46%去除反散射网格。与优化方案相比，次优成像使ED增加了2.75倍（新生儿）和4倍（5岁）。使用优化成像和次优化成像的30分钟后前位透视的估计癌症LAR分别为：0.42%对1.23%（新生儿女性），0.20%对0.53%（新生儿男性），0.47%对1.70%（5岁女性）和0.16%对0.69%（5岁男性）。接受心导管插入术的儿童的辐射相关风险可能很大，但通过优化的成像方法可以显着降低。
To quantify the impact of image optimization on absorbed radiation dose and associated risk in children undergoing cardiac catheterization. Various imaging and fluoroscopy system technical parameters including camera magnification, source-to-image distance, collimation, anti-scatter grids, beam quality, and pulse rates, all affect radiation dose but have not been well studied in younger children. We used anthropomorphic phantoms (ages: newborn and 5-years-old) to measure surface radiation exposure from various imaging approaches and estimated absorbed organ doses and effective doses (ED) using Monte Carlo simulations. Models developed in the National Academies’ Biological Effects of Ionizing Radiation VII report were used to compare an imaging protocol optimized for dose reduction versus suboptimal imaging (+20cm source-to-image-distance, +1 magnification setting, no collimation) on lifetime attributable risk (LAR) of cancer. For the newborn and 5-year-old phantoms respectively ED changes were as follows: +157% and +232% for an increase from 6-inch to 10-inch camera magnification; +61% and +59% for a 20cm increase in source-to-image-distance; −42% and −48% with addition of 1-inch periphery collimation; −31% and −46% with removal of the anti-scatter grid. Compared to an optimized protocol, suboptimal imaging increased ED by 2.75-fold (newborn) and 4-fold (5-year-old). Estimated cancer LAR from 30-minutes of postero-anterior fluoroscopy using optimized versus sub-optimal imaging respectively was: 0.42% versus 1.23% (newborn female), 0.20% vs 0.53% (newborn male), 0.47% versus 1.70% (5-year-old female) and 0.16% vs 0.69% (5-year-old male). Radiation-related risks to children undergoing cardiac catheterization can be substantial but are markedly reduced with an optimized imaging approach.
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影响因子：
2.3
作者：
Brown, PH;Thomas, RD;Johnson, LM
通讯作者：
Johnson, LM
影响因子：
2.3
作者：
Ubeda, Carlos;Vano, Eliseo;Miranda, Patricia
通讯作者：
Miranda, Patricia
影响因子：
19.7
作者：
Miller, DL;Balter, S;Georgia, JD
通讯作者：
Georgia, JD
DOI：
10.1016/j.jvir.2009.04.037
发表时间：
2009-07-01
影响因子：
2.9
作者：
Stecker, Michael S.;Balter, Stephen;Cardella, John F.
通讯作者：
Cardella, John F.
影响因子：
--
作者：
Paquet, F.;Bailey, M. R.;Harrison, J. D.
通讯作者：
Harrison, J. D.