A prospective study of dominance and coronary heart disease in the Normative Aging Study.

A prospective study of dominance and coronary heart disease in the Normative Aging Study.
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规范老龄化研究中的主导地位和冠心病的前瞻性研究。

DOI:
10.1016/s0002-9149(00)00850-x
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发表时间:
2000
期刊:
The American journal of cardiology
影响因子:
--
通讯作者:
Sparrow,D
Sparrow,D
中科院分区:
--
文献类型:
--
作者:
Siegman,AW;Kubzansky,LD;Kawachi,I;Boyle,S;Vokonas,PS;Sparrow,D

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本研究的目的是探讨优势之间的前瞻性关系,由明尼苏达多相人格调查表(MMPI-2)衍生的优势量表,冠心病(CHD)的发病率,独立于参与者的愤怒水平进行评估。该研究是在VA标准老化研究中进行的,这是一项正在进行的老年男性(平均年龄61岁)队列研究。1986年,共有1,225名无冠心病的男性完成了MMPI-2。选择MMPI项目的因素分析提供了基础上的优势规模和愤怒规模的建设。在平均8年的随访中,发生了158例冠心病事件,其中包括29例致死性冠心病,69例非致死性心肌梗死(MI)和60例心绞痛(AP)。与报告最低优势水平(下三分位数)的男性相比,报告最高优势水平(上三分位数)的男性合并非致死性MI和致死性CHD的多变量校正相对风险为1.80(95%置信区间[CI] 1.21至3.24)。愤怒分数的额外调整并没有显着改变这种关系。优势度与AP之间没有显着关系。我们的数据表明,优势是老年男性冠心病的独立危险因素。
The purpose of this study was to examine the prospective relation between dominance, as assessed by a Minnesota Multiphasic Personality Inventory (MMPI-2)-derived dominance scale, and incidence of coronary heart disease (CHD), independent of participants’ anger level. The study was performed in the VA Normative Aging Study, an ongoing cohort of older (mean age 61 years) men. A total of 1,225 men who were free of CHD in 1986 completed the MMPI-2. A factor analysis of selected MMPI items provided the basis for the construction of a dominance scale and an anger scale. During an average of 8 years of follow-up, 158 cases of incident CHD occurred, including 29 cases of fatal CHD, 69 cases of nonfatal myocardial infarction (MI), and 60 cases of angina pectoris (AP). Compared with men reporting the lowest levels of dominance (lower tertile), the multivariate-adjusted relative risk among men reporting the highest levels of dominance (upper tertile) was 1.80 (95% confidence interval [CI] 1.21 to 3.24) for combined nonfatal MI and fatal CHD. Additional adjustment for anger scores did not significantly alter this relation. There was no significant relation between dominance and AP. Our data suggest that dominance is an independent risk factor for CHD in older men.
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