Risk factors for the progression of mild cognitive impairment to dementia.
Risk factors for the progression of mild cognitive impairment to dementia.
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DOI:
10.1016/j.cger.2013.07.009
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发表时间:
2013-11
影响因子:
3.3
通讯作者:
Boustani MA
中科院分区:
文献类型:
--
作者:
Campbell NL;Unverzagt F;LaMantia MA;Khan BA;Boustani MA
As identified in previously published articles, including those published in this issue, the detection of early cognitive impairment among older adult populations is worthy of diagnostic and clinical recognition. Several definitions and classifications have been applied to this form of cognitive impairment over time1–4 including mild cognitive impairment (MCI), 4–6 cognitive impairment no dementia, 7, 8 malignant senescent forgetfulness, 9 and age-associated cognitive decline. 10 Consistent with current usage this review uses the term MCI, and focuses on progression from MCI to dementia.Prevalence estimates of MCI among populations of community-dwelling older adults are as high as 22% of those aged 71 years and older, 11 with prevalence rates among older adults cared for in memory care practices estimated at nearly 40%. 12 The likelihood of progression from MCI to any form of dementia has been suggested to occur at a rate 3 to 5 times higher than those with normal cognition, 4, 13–15 with an annual rate of progression of 12% in the general population and up to 20% in populations at higher risk. 11 As a transitional stage of early cognitive impairment, much attention has been focused on the identification of modifiable and nonmodifiable risk factors to prevent or delay the progression of MCI to dementia.
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DOI:
10.1136/bmj.c3666
发表时间:
2010-07-26
期刊:
BMJ (Clinical research ed.)
影响因子:
--
作者:
Debette S;Markus HS
通讯作者:
Markus HS
DOI:
10.1523/jneurosci.3252-09.2009
发表时间:
2009-12-02
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Fjell AM;Walhovd KB;Fennema-Notestine C;McEvoy LK;Hagler DJ;Holland D;Brewer JB;Dale AM
通讯作者:
Dale AM
影响因子:
11
作者:
Bowler, JV
通讯作者:
Bowler, JV
影响因子:
--
作者:
Brickman, Adam M.;Provenzano, Frank A.;Muraskin, Jordan;Manly, Jennifer J.;Blum, Sonja;Apa, Zoltan;Stern, Yaakov;Brown, Truman R.;Luchsinger, Jose A.;Mayeux, Richard
通讯作者:
Mayeux, Richard
影响因子:
3.4
作者:
Boustani, Malaz A.;Sachs, Greg A.;Callahan, Christopher M.
通讯作者:
Callahan, Christopher M.