Mosquito-repellent controlled-release formulations for fighting infectious diseases.
Mosquito-repellent controlled-release formulations for fighting infectious diseases.
复制标题
用于对抗传染病的驱蚊剂控释制剂。
DOI：
10.1186/s12936-021-03681-7
复制
发表时间：
2021-03-24
期刊：
影响因子：
3
通讯作者：
Kruger T
中科院分区：
文献类型：
--
作者：
Mapossa AB;Focke WW;Tewo RK;Androsch R;Kruger T
在疟疾流行的国家，疟疾是疾病和死亡的主要原因。使用驱蚊剂进行个人防蚊保护可能是一种有用的方法，可以减少和/或预防蚊媒疾病的传播。现有的驱蚊产品，如霜剂、滚抹剂和喷雾剂，用于个人防蚊，缺乏足够的长期功效。在大多数情况下，它们需要经常重新应用或更换。驱避剂从几种基质中的包封和释放已经上升为开发基于驱避剂的系统的发明的替代方法。目前的工作回顾了各种研究的发展和使用驱避剂控释制剂，如聚合物微胶囊，聚合物微孔制剂，聚合物胶束，纳米乳液，固体脂质纳米颗粒，脂质体和环糊精作为新的工具，在室外环境中的蚊媒疟疾控制。此外，调查的数学建模用于驱避剂的释放速率进行了深入讨论，通过探索Higuchi，Korsmeyer-Peppas，Weibull模型，以及最近开发的Mapossa模型。因此，搜索的研究表明，最终的驱虫剂产品不仅应有效对抗疟疾寄生虫的蚊子媒介，而且还应减少其他传播疾病的蚊子的叮咬频率，如登革热，基孔肯雅热，黄热病和寨卡病毒。这样，它们将有助于改善整体公共卫生和社会福祉。在线版本包含补充材料，可通过10.1186/s12936-021-03681-7获得。
Malaria is a principal cause of illness and death in countries where the disease is endemic. Personal protection against mosquitoes using repellents could be a useful method that can reduce and/or prevent transmission of mosquito-borne diseases. The available repellent products, such as creams, roll-ons, and sprays for personal protection against mosquitoes, lack adequate long-term efficacy. In most cases, they need to be re-applied or replaced frequently. The encapsulation and release of the repellents from several matrices has risen as an alternative process for the development of invention of repellent based systems. The present work reviews various studies about the development and use of repellent controlled-release formulations such as polymer microcapsules, polymer microporous formulations, polymer micelles, nanoemulsions, solid-lipid nanoparticles, liposomes and cyclodextrins as new tools for mosquito-borne malaria control in the outdoor environment. Furthermore, investigation on the mathematical modelling used for the release rate of repellents is discussed in depth by exploring the Higuchi, Korsmeyer-Peppas, Weibull models, as well as the recently developed Mapossa model. Therefore, the studies searched suggest that the final repellents based-product should not only be effective against mosquito vectors of malaria parasites, but also reduce the biting frequency of other mosquitoes transmitting diseases, such as dengue fever, chikungunya, yellow fever and Zika virus. In this way, they will contribute to the improvement in overall public health and social well-being. The online version contains supplementary material available at 10.1186/s12936-021-03681-7.
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DOI：
10.2987/8756-971x(2005)21
发表时间：
2005-09-01
影响因子：
1
作者：
Grieco, JP;Achee, NL;Andre, RG
通讯作者：
Andre, RG
影响因子：
5.7
作者：
Bezerra, Fabricio Maesta;Garcia Carmona, Oscar;de Moraes, Flavio Faria
通讯作者：
de Moraes, Flavio Faria
影响因子：
2.1
作者：
Barnard, DR;Xue, RD
通讯作者：
Xue, RD
影响因子：
5.5
作者：
BURGHARDT, WR
通讯作者：
BURGHARDT, WR
影响因子：
4.4
作者：
Bezerra, Fabricio Maesta;Garcia Carmona, Oscar;Lis, Manuel
通讯作者：
Lis, Manuel