Functional Networks for Social Communication in the Macaque Monkey.

Functional Networks for Social Communication in the Macaque Monkey.
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DOI:
10.1016/j.neuron.2018.06.027
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发表时间:
2018-07-25
期刊:
影响因子:
16.2
通讯作者:
Freiwald WA
Freiwald WA
中科院分区:
医学1区
文献类型:
--
作者:
Shepherd SV;Freiwald WA

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所有灵长类动物都会交流。为了剖析社会交流的神经回路,我们使用功能磁共振成像(fMRI)绘制了非人类灵长类动物的社会感知、第二人称(互动)社会认知和面部运动产生的大脑区域。面部感知、第二人称认知和面部运动网络在很大程度上不重叠,作为不同的功能单元,而不是一个集成的前馈处理管道。第二人称情境选择性地参与前额叶皮层内侧的一个区域,而口面运动的产生则涉及前额叶皮层内侧、外侧和岛叶皮层的皮质下和皮质区域。这些区域沿中外侧轴表现出一定的专门化,但没有分离。嘴唇运动的产生招募了包括假定的布洛卡区同源物在内的区域。这些发现为社会交流的神经结构提供了一个新的视角,并表明由外侧运动前皮层产生的表达性口面部运动是人类语言的一个假定的进化先驱。Shepherd和Freiwald研究了猴子在模拟社会互动中交流的神经关联,发现猴子大脑中社会认知和社会信号产生的网络与人类语言产生的网络惊人地相似。
All primates communicate. To dissect the neural circuits of social communication, we used fMRI to map non-human primate brain regions for social perception, 2nd person (interactive) social cognition, and orofacial movement generation. Face perception, 2nd person cognition, and face motor networks were largely non-overlapping and acted as distinct functional units rather than an integrated feedforward-processing pipeline. While 2nd person context selectively engaged one region in medial prefrontal cortex, production of orofacial movements recruited distributed subcortical and cortical areas in medial and lateral frontal and insular cortex. These areas exhibited some specialization, but not dissociation, of function along the medio-lateral axis. Production of lipsmack movements recruited areas including putative homologs of Broca’s area. These findings provide a new view of the neural architecture for social communication, and suggest expressive orofacial movements generated by lateral premotor cortex as a putative evolutionary precursor to human speech. Shepherd & Freiwald examine the neural correlates of communication in monkeys during a simulated social interaction, discovering networks in the monkey brain for social cognition and social signal production, with surprising similarities to those producing human speech.
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