Anatomical Connections of the Functionally Defined "Face Patches" in the Macaque Monkey.

Anatomical Connections of the Functionally Defined "Face Patches" in the Macaque Monkey.
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猕猴中功能定义的“面部斑块”的解剖连接。

DOI:
10.1016/j.neuron.2016.05.009
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发表时间:
2016-06-15
期刊:
影响因子:
16.2
通讯作者:
Tsao D
Tsao D
中科院分区:
医学1区
文献类型:
--
作者:
Grimaldi P;Saleem KS;Tsao D

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人脸识别背后的神经回路为理解视觉对象表征、社会认知和分层信息处理提供了模型。迄今为止缺乏的一个基本信息是面部斑块的详细解剖连接。在这里,我们将逆行示踪剂注射到四个不同的面部斑块(PL、ML、AL、AM)中,以表征它们的解剖连接性。我们发现,这些小块之间有着强烈而特异的联系,单个小块接受来自纹外皮层、内侧颞叶和三个皮层下结构(枕、屏状核和杏仁核)的输入。来自前额叶皮层的输入出奇地微弱。斑块在前馈和反馈方向上彼此紧密相连,与串行层次结构不一致。这些结果提供了第一个直接的解剖学证据,面部斑块构成了一个高度专业化的系统,并表明,皮层下区域可能发挥了至关重要的作用,在路由面部相关的信息,以随后的处理阶段。
The neural circuits underlying face recognition provide a model for understanding visual object representation, social cognition, and hierarchical information processing. A fundamental piece of information lacking to date is the detailed anatomical connections of the face patches. Here, we injected retrograde tracers into four different face patches (PL, ML, AL, AM) to characterize their anatomical connectivity. We found that the patches are strongly and specifically connected to each other, and individual patches receive inputs from extrastriate cortex, the medial temporal lobe, and three subcortical structures (the pulvinar, claustrum, and amygdala). Inputs from prefrontal cortex were surprisingly weak. Patches were densely interconnected to one another in both feedforward and feedback directions, inconsistent with a serial hierarchy. These results provide the first direct anatomical evidence that the face patches constitute a highly specialized system, and suggest that subcortical regions may play a vital role in routing face-related information to subsequent processing stages.
DOI: 10.1126/science.1194908
发表时间: 2010-11-05
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Freiwald WA;Tsao DY
通讯作者: Tsao DY
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