Advances in HIV microbicide development.
Advances in HIV microbicide development.
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DOI：
10.4155/fmc.11.153
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发表时间：
2011-12
影响因子：
4.2
通讯作者：
Dewhurst S
中科院分区：
文献类型：
--
作者：
Olsen JS;Easterhoff D;Dewhurst S
There is an urgent need for a way to control the spread of the global HIV pandemic. A microbicide, or topical drug applied to the mucosal environment to block transmission, is a promising HIV prevention strategy. The development of a safe and efficacious microbicide requires a thorough understanding of the mucosal environment and it's role in HIV transmission. Knowledge of the key events in viral infection identifies points at which the virus might be most effectively targeted by a microbicide. The cervicovaginal and rectal mucosa play an important role in the innate defense against HIV, and microbicides must not interfere with these functions. In this review we discuss the current research on HIV microbicide development.
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影响因子：
56.3
作者：
Cutler, Blayne;Justman, Jessica
通讯作者：
Justman, Jessica
DOI：
10.1038/nri2394
发表时间：
2008-09
期刊：
Nature reviews. Immunology
影响因子：
--
作者：
Fish EN
通讯作者：
Fish EN
影响因子：
56.9
作者：
COCCHI, F;DEVICO, AL;LUSSO, P
通讯作者：
LUSSO, P
影响因子：
82.9
作者：
Bomsel, M
通讯作者：
Bomsel, M
DOI：
10.1097/qad.0b013e32833424c8
发表时间：
2010-01-16
期刊：
AIDS (London, England)
影响因子：
--
作者：
Anderson DJ;Politch JA;Nadolski AM;Blaskewicz CD;Pudney J;Mayer KH
通讯作者：
Mayer KH