Comparative Analysis of Biological Activity of Artificial and Wild Agarwood
Comparative Analysis of Biological Activity of Artificial and Wild Agarwood
复制标题
人工与野生沉香生物活性对比分析
作者：
马生;乔梦吉;符韵林;韦鹏练;李英健;刘志高
沉香是一种具有广泛用途的高度经济重要的药用植物;然而，人工和野生沉香的生物活性之间的差异尚不清楚。本研究以真菌生产的沉香和天然沉香的醇溶性提取物为研究对象，测定其总体生物活性的差异。采用紫外-可见分光光度法测定其抗氧化能力（DPPH、ABTS+清除率和总还原力）、抗乙酰胆碱酯酶和抗α-葡萄糖苷酶活性。结果表明，在2 mg/mL醇溶物浓度下，人工沉香对DPPH自由基的清除率为野生沉香的93.74-102.31%，对ABTS+自由基的清除率为天然沉香的75.38-95.52%。当醇溶性浸出物浓度为3.5mg/mL时，人工沉香样品的总还原力为野生沉香的63.07-80.29%。当醇提物浓度为4 mg/mL时，人工沉香样品的乙酰胆碱酯酶活性抑制率为野生沉香的102.56-109.16%。在1 mg/mL醇溶性提取物浓度下，人工沉香样品对α-葡萄糖苷酶活性的抑制率为野生沉香的68.32-100.39%。
Agarwood is a highly economically important medicinal herb with widespread uses; however, the difference between the biological activities of artificial and wild agarwood is unclear. In this study, the alcohol-soluble extracts of agarwood produced by fungi and natural agarwood were used to determine the differences between the overall biological activities. The antioxidant ability (the clearance rates of 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+) radicals, and total reducing power), anti-acetylcholinesterase, and anti-α-glucosidase activity were determined by ultraviolet-visible spectrophotometry. The results indicated that with 2 mg/mL alcohol-soluble extracts, the scavenging DPPH radical rates of the artificial agarwood samples were 93.74–102.31% of that of the wild agarwood, and the ABTS+ radical clearance rates of the artificial agarwood samples were 75.38–95.52% of that of the natural agarwood. With 3.5 mg/mL alcohol-soluble extracts, the artificial agarwood samples had a total reducing power of 63.07–80.29% of that of the wild agarwood. With 4 mg/mL alcohol-soluble extract, the acetylcholinesterase activity inhibition rates of the artificial agarwood samples were 102.56–109.16% of that of the wild agarwood. With 1 mg/mL alcohol soluble extracts, the α-glucosidase effect inhibitions rates of the artificial agarwood samples were 68.32–100.39% of that of the wild agarwood.
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影响因子：
2
作者：
Canhong Wang;Shuai Wang;Deqian Peng;Zhangxin Yu;Peng Guo;Jianhe Wei
通讯作者：
Canhong Wang;Shuai Wang;Deqian Peng;Zhangxin Yu;Peng Guo;Jianhe Wei
影响因子：
3.8
作者：
Mi, Cheng-neng;Yuan, Jing-zhe;Dai, Hao-fu
通讯作者：
Dai, Hao-fu
DOI：
--
发表时间：
2008
期刊：
--
影响因子：
--
作者：
N. Azah;A. Abusaid;Abd. Majid J. Saidatul Husni;N. Hasnida;N. Yasmin
通讯作者：
N. Azah;A. Abusaid;Abd. Majid J. Saidatul Husni;N. Hasnida;N. Yasmin
DOI：
10.1080/14756366.2019.1576657
发表时间：
2019-01-01
影响因子：
5.6
作者：
Yang, Li;Yang, Yi-Ling;Dai, Hao-Fu
通讯作者：
Dai, Hao-Fu
影响因子：
2.7
作者：
Sin-Ling Wang;Hsiang‐Ruei Liao;M. Cheng;Chih-Wen Shu;Chun-Lin Chen;M. Chung;Jih-Jung Chen
通讯作者：
Sin-Ling Wang;Hsiang‐Ruei Liao;M. Cheng;Chih-Wen Shu;Chun-Lin Chen;M. Chung;Jih-Jung Chen