Theta band network supporting human episodic memory is not activated in the seizure onset zone.
Theta band network supporting human episodic memory is not activated in the seizure onset zone.
复制标题
支持人类情景记忆的θ波频段网络在癫痫发作起始区未被激活。
DOI:
10.1016/j.neuroimage.2018.08.052
复制
发表时间:
2018-12
期刊:
影响因子:
5.7
通讯作者:
Baxter MG
中科院分区:
文献类型:
--
作者:
Young JJ;Rudebeck PH;Marcuse LV;Fields MC;Yoo JY;Panov F;Ghatan S;Fazl A;Mandelbaum S;Baxter MG
Episodic memory, everyday memory for events, is frequently impaired in patients with epilepsy. We tested patients undergoing intracranial electroencephalography (intracranial EEG) monitoring for the treatment of medically-refractory epilepsy on a well-characterized paradigm that requires episodic memory. We report that an anatomically diffuse network characterized by theta-band (4–7 Hz) coherence is activated at the time of target selection in a task that requires episodic memory. This distinct network of oscillatory activity is absent when episodic memory is not required. Further, the theta band synchronous network was absent in electrodes within the patient’s seizure onset zone (SOZ). Our data provide novel empirical evidence for a set of brain areas that supports episodic memory in humans, and it provides a pathophysiologic mechanism for the memory deficits observed in patients with epilepsy.
登录
查看更多内容
影响因子:
5.3
作者:
Foster, Brett L.;Kaveh, Anthony;Parvizi, Josef
通讯作者:
Parvizi, Josef
影响因子:
4.3
作者:
Klein A;Tourville J
通讯作者:
Tourville J
影响因子:
4.8
作者:
Sutula, TP;Hagen, J;Pitkänen, A
通讯作者:
Pitkänen, A
影响因子:
3.4
作者:
Mitra, PP;Pesaran, B
通讯作者:
Pesaran, B
影响因子:
--
作者:
Oostenveld R;Fries P;Maris E;Schoffelen JM
通讯作者:
Schoffelen JM