Cell cycle perturbations induced by human herpesvirus 6 infection and their effect on virus replication.
Cell cycle perturbations induced by human herpesvirus 6 infection and their effect on virus replication.
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人疱疹病毒6感染引起的细胞周期扰动及其对病毒复制的影响
DOI:
10.1007/s00705-013-1826-0
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发表时间:
2014-03
影响因子:
2.7
通讯作者:
Yao K
中科院分区:
文献类型:
--
作者:
Li L;Gu B;Zhou F;Chi J;Feng D;Xie F;Wang F;Ma C;Li M;Wang J;Yao K
In this study, we demonstrate that infection of HSB-2 cells with human herpesvirus 6 (HHV-6) resulted in the accumulation of infected cells in the G2/M phase of the cell cycle. Analysis of various cell-cycle-regulatory proteins indicated that the levels of cyclins A2, B1, and E1 were increased in HHV-6-infected cells, but there was no difference in cyclin D1 levels between mock-infected and HHV-6-infected cells. Our data also showed that inducing G2/M phase arrest in cells infected by HHV-6 provided favorable conditions for viral replication.
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DOI:
10.1074/jbc.m009731200
发表时间:
2001-05-18
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Lim KP;Liu DX
通讯作者:
Liu DX
影响因子:
5.4
作者:
Morita, E;Tada, K;Sugamura, K
通讯作者:
Sugamura, K
影响因子:
5.4
作者:
Dove, B;Brooks, G;Hiscox, JA
通讯作者:
Hiscox, JA
影响因子:
12.7
作者:
Li, Lingyun;Gu, Bin;Yao, Kun
通讯作者:
Yao, Kun
影响因子:
12.7
作者:
Cameron, Barbara;Flamand, Louis;Lloyd, Andrew
通讯作者:
Lloyd, Andrew