An in vitro simulation method for the tribological assessment of complete natural hip joints.
An in vitro simulation method for the tribological assessment of complete natural hip joints.
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DOI：
10.1371/journal.pone.0184226
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Williams S
中科院分区：
文献类型：
--
作者：
Groves D;Fisher J;Williams S
文献中广泛报道了使用髋关节模拟器来评价全髋关节置换术的摩擦学性能，然而，研究天然髋关节摩擦学的体外模拟研究有限，报告了不同的方法。本研究成功开发了一种用于完整自然髋关节的体外模拟系统，该系统能够在保持正确关节旋转中心的同时以不同方向定位髋臼和股骨头。通过在摆锤摩擦模拟器中测试完整的、匹配的天然猪髋关节和猪髋关节半关节置换术关节来评估模拟系统的有效性。结果显示了双相润滑的证据，在两组中均观察到摩擦的非线性增加。完全天然关节组中总体平均摩擦系数值较低，随时间推移以较低速率增加，表明与髋关节半置换术关节相比，完全天然髋关节中液体渗出和向固相润滑的转变发生得更慢。据设想，这种方法将被用来调查发展髋关节骨关节炎的形态风险因素，以及早期介入治疗退行性髋关节疾病的有效性。
The use of hip joint simulators to evaluate the tribological performance of total hip replacements is widely reported in the literature, however, in vitro simulation studies investigating the tribology of the natural hip joint are limited with heterogeneous methodologies reported. An in vitro simulation system for the complete natural hip joint, enabling the acetabulum and femoral head to be positioned with different orientations whilst maintaining the correct joint centre of rotation, was successfully developed for this study. The efficacy of the simulation system was assessed by testing complete, matched natural porcine hip joints and porcine hip hemiarthroplasty joints in a pendulum friction simulator. The results showed evidence of biphasic lubrication, with a non-linear increase in friction being observed in both groups. Lower overall mean friction factor values in the complete natural joint group that increased at a lower rate over time, suggest that the exudation of fluid and transition to solid phase lubrication occurred more slowly in the complete natural hip joint compared to the hip hemiarthroplasty joint. It is envisaged that this methodology will be used to investigate morphological risk factors for developing hip osteoarthritis, as well as the effectiveness of early interventional treatments for degenerative hip disease.
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影响因子：
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发表时间：
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