Psychological well-being and risk of dementia.

Psychological well-being and risk of dementia.
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DOI:
10.1002/gps.4849
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发表时间:
2018-05
影响因子:
4
通讯作者:
Terracciano A
Terracciano A
中科院分区:
医学2区
文献类型:
--
作者:
Sutin AR;Stephan Y;Terracciano A

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幸福感是一种心理资源,可以缓冲与年龄相关的疾病。我们测试这种保护作用是否延伸到痴呆症,以及它是否独立于痛苦。参与者(N=10,099)来自健康和退休研究。积极心理功能的五个方面(生活满意度、乐观、掌握、生活目标、积极情感)被测试为6-8年后痴呆事件的预测因子。生活目标与痴呆症风险降低30%相关,与心理困扰、其他临床和行为风险因素、收入/财富和遗传风险无关。在控制了痛苦和其他风险因素后,幸福感的其他方面与痴呆症风险无关。在考虑了心理痛苦后,我们发现幸福的衡量标准通常不能预防痴呆症的风险。唯一的例外是生活的目的,这表明有意义和目标驱动的生活可以降低患痴呆症的风险。
Well-being is a psychological resource that buffers against age-related disease. We test whether this protective effect extends to dementia and whether it is independent of distress. Participants (N=10,099) were from the Health and Retirement Study. Five aspects of positive psychological functioning (life satisfaction, optimism, mastery, purpose in life, positive affect) were tested as predictors of incident dementia over 6–8 years. Purpose in life was associated with a 30% decreased risk of dementia, independent of psychological distress, other clinical and behavioral risk factors, income/wealth, and genetic risk. After controlling for distress and other risk factors, the other aspects of well-being were not associated with dementia risk. After considering psychological distress, we found that measures of well-being were generally not protective against risk of dementia. The one exception is purpose in life, which suggests that a meaningful and goal-driven life reduces risk of dementia.
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